腹水超滤浓缩回输治疗肝硬化顽固性腹水的临床效果  

Clinical Effect of Ultrafiltration Concentration and Reinfusion of Ascites in the Treatment of Refractory Ascites Due to Cirrhosis

作　　者：李梅 LI Mei(Department of Gastroenterology,Honghe First People's Hospital,Jianshui,Yunnan Province,661100 China)

机构地区：[1]红河州第一人民医院消化内科,云南建水661100

出　　处：《中外医疗》2020年第6期45-47,共3页China & Foreign Medical Treatment

摘　　要：目的探究腹水超滤浓缩回输治疗肝硬化顽固性腹水的临床效果。方法方便选取2017年1月-2019年1月到该院就诊的肝硬化顽固性腹水患者90例作为研究对象,采用奇偶分组法进行分组,每组患者为45例,实验组患者采用腹水超滤浓缩回输治疗,对照组患者采用腹腔穿刺放水治疗,对比两组患者的治疗有效率、腹部尺寸、体重、尿量、治疗前后血浆白蛋白、腹水白蛋白的变化情况。结果实验组患者的治疗有效率(93.33%)显著高于对照组(77.78%),差异有统计学意义(χ~2=4.406,P=0.000);实验组患者的腹部尺寸、体重、尿量变化情况(64.28±5.14)cm、(56.24±2.19)kg、(1 438.25±236.19)mL和对照组(78.25±3.97)cm、(63.47±3.67)kg、(1 026.81±194.28)mL对比,差异有统计学意义(t=14.429、11.348、9.025,P<0.05);治疗前,实验组患者的血浆白蛋白、腹水白蛋白(6.05±1.02)g/L、(28.91±2.15)g/L和对照组(5.98±0.99)g/L、(28.72±3.48)g/L对比,差异无统计学意义(t=0.330、0.312,P=0.742,0.756);治疗后,实验组患者的血浆白蛋白、腹水白蛋白变化情况(48.65±3.09)g/L、(35.99±1.43)g/L显著优于对照组(45.37±2.15)g/L、(33.29±1.16)g/L,差异有统计学意义(t=5.845、9.836,P<0.05)。结论腹水超滤浓缩回输治疗肝硬化顽固性腹水效果显著,可明显改善患者的血浆白蛋白、腹水白蛋白含量,该种治疗方式值得在临床中推广。Objective To explore the clinical effect of ascites ultrafiltration concentration and reinfusion in the treatment of refractory ascites due to cirrhosis. Methods Ninety patients with intractable ascites of cirrhosis who came to the hospital from January 2017 to January 2019 were convenient selected as the research objects. They were divided into two groups by odd and even grouping method. Each group had 45 cases. The experimental group was treated by ultrafiltration and concentrated reinfusion of ascites, while the control group was treated by abdominal puncture and drainage. Effectiveness of treatment, abdominal size, weight, urine volume, changes of plasma albumin and ascites albumin before and after treatment.Results The treatment efficiency of patients in the experimental group(93.33%) was significantly higher than that in the control group(77.78%), and the difference was statistically significant(χ~2=4.406, P=0.000);changes in abdominal size,weight, and urine output of patients in the experimental group(64.28±5.14)cm,(56.24±2.19)kg,(1 438.25±236.19)mL and the control group(78.25±3.97)cm,(63.47±3.67)kg,(1 026.81±194.28)mL,and the difference was statistically significant(t=14.429, 11.348, 9.025,P<0.05);before treatment, the plasma albumin and ascites albumin of the experimental group(6.05±1.02)g/L,(28.91 ±2.15)g/L and the control group(5.98 ±0.99)g/L,(28.72 ±3.48)g/L were not significantly different(t =0.330,0.312, P =0.742, 0.756);after treatment, the changes in plasma albumin and ascites albumin in the experimental group(48.65±3.09)g/L,(35.99±1.43)g/L were significantly better than those in the control group(45.37±2.15)g/L,(33.29±1.16)g/L,which had statistical significance(t=5.845, 9.836, P<0.05). Conclusion Ultrafiltration concentration and reinfusion of ascites can significantly improve the content of plasma albumin and ascites albumin in patients with refractory ascites due to liver cirrhosis, which is worth promoting in clinical practice.

关 键 词：腹水超滤浓缩回输 肝硬化 顽固性 腹水 临床效果 

分 类 号：R575[医药卫生—消化系统]