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作 者:YU Bin-yan WANG Yan-ping SHANG Hong-cai WANG Li-ying WAN Yi-jia ZHAO Chen XUAN Li-hua
机构地区:[1]Department of Acupuncture and Moxibustion,The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou(310000),China [2]Institute of Basic Research in Clinical Medicine,China Academ y of Chinese Medical Sciences,Beijing(100700),China [3]Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Beijing University of Chinese Medicine Affiliated D ongzhim en Hospital,Beijing(100700),China [4]The Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin(300193),China
出 处:《Chinese Journal of Integrative Medicine》2020年第6期455-461,共7页中国结合医学杂志(英文版)
基 金:Supported by the Scientific Research Special Fund of Traditional Chinese Medicine Industry(No.201507006-01)。
摘 要:Objective:To compare the clinical effects of thick-needle therapy(TNT)and acupuncture therapy(AT)on patients with Bell's palsy(BP)at the recovery stage.Methods:A total of 146 eligible participants from 3 hospitals in China were randomized into the TNT group(73 cases)and the AT group(73 cases)using a central randomization.Both groups received Western medicine thrice a day for 4 weeks.Moreover,patients in the TNT group received subcutaneous insertion of a thick needle into Shendao(GV 11)acupoint,while patients in the AT group received AT at acupoints of Cuanzhu(BL 2),Yangbai(GB 14),Dicang(ST 4),Xiaguan(ST 7),Jiache(ST 6),Yingxiang(LI 20)and Hegu(LI 4),4 times a week,for 4 weeks.Both groups received 2 follow-up visits,which were arranged at 1 month and 3 months after treatment,respectively.The primary outcome measure was House-Brackmann Facial Nerve Grading System(HBFNGS)grade.And the clinical recovery rates of both groups were evaluated according to the HBFNGS grades after treatment.The secondary outcome measures included the facial disability index(FDI)and electroneurogram(EnoG).The adverse events were observed and recorded in both groups.Results:Three cases withdrew from the trial,2 in the TNT group and 1 in the AT group.There was no significant difference in the clinical recovery rates between the TNT and AT groups after 4-week treatment[40.85%(29/71)vs.34.72%(25/72),P>0.05].At the 2nd follow-up visit,more patients in the TNT group showed reduced HBFNGS grades than those in the AT group(P<0.01).No significant difference was observed between the two groups in FDI score,EnoG latency and maximum amplitude ratio at all time points(all P>0.05).Conclusion:The clinical effect of TNT was equivalent to that of AT in patients with BP at recovery stage,while the post-treatment effect of TNT was superior to that of AT.
关 键 词:Bell's palsy ACUPUNCTURE thick-needle therapy randomized controlled trial Chinese medicine
分 类 号:R745.12[医药卫生—神经病学与精神病学]
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