补肾填精益髓法治疗缺血性中风轻度认知功能障碍肾虚髓减证临床研究  

Clinical Study on Treatment of Mild Cognitive Impairment in Patients with Ischemic Stroke by Kidney-nourishing,Essence-replenishing and Marrow-tonifying Method

作　　者：单金平[1] 单晓晶[1] 徐云龙[2] 石天竹 贾子岳 SHAN Jinping;SHAN Xiaojing;XU Yunlong;SHI Tianzhu;JIA Ziyue(Shenyang Central Hospital,Shenyang 110004,Liaoning,China;Affiliated Hospital of Changchun University of Traditional Chinese Medicine,Changchun 130021,Jilin,China;Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

机构地区：[1]沈阳市中医院,辽宁沈阳110004 [2]长春中医药大学附属医院,吉林长春130021 [3]辽宁中医药大学,辽宁沈阳110847

出　　处：《辽宁中医药大学学报》2020年第3期151-154,共4页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2015047);吉林省中医药科技项目(2017189)。

摘　　要：目的探析补肾填精益髓法治疗缺血性中风轻度认知功能障碍肾虚髓减证的临床疗效。方法将74例缺血性中风轻度认知功能障碍肾虚髓减证的患者随机分为治疗组与对照组各37例,两组患者均给予西医常规治疗,治疗组在此基础上加用补肾填精益髓法。两组患者治疗前后均检测简易智能量表(MMSE)、蒙特利尔量表(MoCA)、日常生活能力量表(ADL)和临床疗效评价,治疗4周后评价疗效。结果在临床疗效方面,治疗组总有效率89.19%,对照组总有效率67.57%,两组患者总有效率比较差异有统计学意义(P<0.05),治疗组优于对照组;在MMSE评分方面,两组患者比较差异有统计学意义(P<0.05),治疗组优于对照组;在MoCA评分方面,两组患者比较差异有统计学意义(P<0.01),治疗组明显优于对照组;在ADL评分方面,两组患者比较差异有统计学意义(P<0.01),治疗组明显优于对照组。结论补肾填精益髓法治疗缺血性中风轻度认知功能障碍肾虚髓减证疗效显著,能显著改善患者认知能力及患者的生活质量,值得临床推广。Objective To explore the clinical efficacy of kidney-nourishing,essence-replenishing and marrow-tonifying method in the treatment of mild cognitive impairment syndrome in patients with ischemic stroke.Methods 74 patients with mild cognitive impairment in ischemic stroke were randomly divided into two groups:treatment group and control group(37 cases in each group).The patients in the two groups were treated by routine Western medicine.The simple intelligence scale(MMSE),Montreal scale(MoCA),daily life capacity scale(ADL)and clinical efficacy were measured before and after treatment in both groups and the efficacy was evaluated after 4 weeks of treatment.Results In terms of clinical efficacy,the total effective rate was 89.19%in the treatment group and 67.57%in the control group.There was a difference in the total effective rate between the two groups(P<0.05).The treatment group was superior to the control group.In the MMSE score,there was difference between the two groups(P<0.05),and the treatment group was superior to the control group;There was significant difference in MoCA scores between the two groups(P<0.01),and the treatment group was significantly better than the control group.There was significant difference in ADL scores between the two groups(P<0.01)and the treatment group was significantly superior to the control group.Conclusion Kidney-nourishing,essence-replenishing and marrow-tonifying method is effective in treating mild cognitive impairment in patients with ischemic stroke,and can significantly improve the cognitive ability and quality of life.It is worthy of clinical promotion.

关 键 词：补肾填精益髓法 缺血性中风 轻度认知功能障碍 肾虚髓减证 临床研究 

分 类 号：R743.3[医药卫生—神经病学与精神病学]