视频脑电图在早产儿脑损伤诊断中的应用研究  

Analysis of diagnostic value of VEEG on brain injury in premature infants

作　　者：郑侠 黑明燕 方方[2] 李华[2] 董世霄 郑旭 刘颖 Zheng Xia;Hei Mingyan;Fang Fang;Li Hua;Dong Shixiao;Zheng Xu;Liu Ying(Neonatal Center,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,China)

机构地区：[1]国家儿童医学中心首都医科大学附属北京儿童医院新生儿中心,100045 [2]国家儿童医学中心首都医科大学附属北京儿童医院神经内科,100045

出　　处：《北京医学》2020年第4期310-312,316,共4页Beijing Medical Journal

摘　　要：目的探讨不同时间点床旁视频脑电图(video electroencephalogram,VEEG)监测对判断早产儿脑损伤的应用价值。方法选取2016年12月至2017年10月于首都医科大学附属北京儿童医院新生儿重症监护室(newborn intensive care unit,NICU)住院,出院后在新生儿科和神经康复中心进行随访的早产儿39例。根据住院期间头颅B超结果,将患儿分为早产儿脑损伤组和非脑损伤组,收集基本资料,分别在日龄(day of life,DOL)1周,纠正胎龄(correct age,CA)40周、44周及52周时各进行1次VEEG检查,每次2~3 h;对比分析两组早产儿发生脑损伤的情况及VEEG特点。结果早产儿脑损伤组16例,非脑损伤组23例。仅DOL 1周时的VEEG结果与脑损伤有相关性(P<0.05)。早产儿随日龄增大,VEEG结果趋于正常。结论早期应用VEEG结合床旁头颅B超评估,可辅助评估早产儿脑损伤情况,给予高风险患儿早期干预以减少脑损伤的危害。Objective To study the clinical value of video electroencephalogram(VEEG)at different time point on the diagnosis of brain injury in premature infants.Methods Retrospective analysis was conducted on children hospitalized at Department of NICU Beijing Children’s Hospital and followed up at Department fo Neonatology and Neurological Rehabilitation Center from December 2016 to October 2017.Patients were classified to brian injury group and no brian injury group according to the cranial ultrasound results during hospitalization.Basic information of patients were collected.VEEG tests were performed at day of live(DOL)one week,correct age(CA)40 week,44 week and 52 week,respectively.Each test persisted 2-3 hours.The correlations between brain injury status and VEEG results in the two groups were analyzed.Results Data from39 premature infants were included,16 in brain injury group and 23 in no brain injury group.Only VEEG at DOL one week significantly related to brain injury(P<0.05).Following the increase of DOL in premature infants,the VEEG results tended to be normal.Conclusions Early perform of VEEG and cranial ultrasound could help early evaluation of brain injury in premature infants.Given interventional treatment to high risk infants can decrease the risk of brain injury.

关 键 词：早产儿 脑损伤 视频脑电图 头颅B超 

分 类 号：R722.6[医药卫生—儿科]