hSnd2/TMEM208 is an HIF-1α-targeted gene and contains a WH2 motif  

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作  者:Pinggui Lei Yan Xiao Pei Li Peng Xie Huilin Wang Shoujun Huang Pingping Song Yuanbo Zhao 

机构地区:[1]Department of Radiology,The Affiliated Hospital of Guizhou Medical University,Guiyang 550004,China [2]Department of Chemical Biology,School of Biology and Engineering,Guizhou Medical University,Guiyang 550025,China [3]Department of Breast Surgery,Cancer Hospital of Guizhou Medical University,Guiyang 550000,China [4]Key Laboratory of Molecular Biology of Guizhou Medical University and Education Ministry Key Laboratory of Endemic and Minority Diseases,Guiyang 550004,China [5]Center for Developmental Biology,School of Life Sciences,Anhui Agricultural University,Hefei 230000,China [6]Medical Biotechnology Center of Guizhou,Guizhou Medical University,Guiyang 550025,China [7]School of Basic Medicine,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China

出  处:《Acta Biochimica et Biophysica Sinica》2020年第3期328-331,共4页生物化学与生物物理学报(英文版)

基  金:supported by the grants from the National Nature Science Foundation of China(Nos.31501118,81960338,and 31760325);the Joint Foundation of Guiyang Science and Technology Bureau and Guizhou Medical University(No.(2017)30-22)to Y.Z.;the Doctoral Research Initiation Fund of the Affiliated Hospital of Guizhou Medical University and the Joint Fund of Guizhou Province Department of Science and Technology(No.Qiankehe LH(2017)7208)to P.L.

摘  要:Eukaryotic cells have multiple membrane organelles within the cell.One of the cellular challenges is to direct proteins,especially membrane proteins,to the right membrane compartment.Around onethird of the encoded proteins must be targeted to the endoplasmic reticulum(ER)before being trafficked into the right organelles[1].

关 键 词:TARGETED reticulum TRAFFIC 

分 类 号:Q2[生物学—细胞生物学]

 

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