2例阑尾类癌临床病理分析  

Clinicopathologic analysis for 2 cases of appendiceal carcinoid

作　　者：刘学蓉[1] 白霜 伍静 LIU Xuerong;BAI Shuang;WU Jing(Department of Pathology,Second People’s Hospital of Xindu District,Sichuan 610501,China)

机构地区：[1]成都市新都区第二人民医院病理科,成都610501

出　　处：《临床与病理杂志》2020年第5期1326-1329,共4页Journal of Clinical and Pathological Research

摘　　要：采用大体检查、光学显微镜及免疫组织化学等方法对2例阑尾类癌进行临床病理回顾性分析。2例阑尾类癌患者术前均有阑尾炎的典型症状,临床诊断均为阑尾炎,术后病理肉眼观察与一般的阑尾炎无明显差异,中段至尖端不均匀增粗,切面未见明显占位性病变。按《临床技术操作规范·病理学分册》常规取材,阑尾根部、中段和尖端各取1块。显微镜下阑尾黏膜下、肌层及浆膜层见少许零散的异型细胞团,均补取材,补取组织中异型细胞团明显增多,最后2例病理诊断均为阑尾类癌伴阑尾炎。阑尾类癌发病率低,漏诊率高。因此,病理医生取材时应注意观察阑尾的大体情况,对于增粗的部分要多取材,甚至将全部标本送检,不要机械性地常规取3块;阅片时一定要仔细,不要局限于低倍镜,尽量减少漏诊。Two cases of appendiceal carcinoid were retrospectively analyzed by gross examination,light microscopy and immunohistochemistry.They are typical symptoms of appendicitis before operation in these two cases,and the clinical diagnosis is appendicitis.There is no significant difference of the pathological observation between it and general appendicitis after operation.These two appendices unevenly thicken from the midpiece to the tip,with no obvious space-occupying lesions on the section.Conventionally sampling a piece from the root,middle and tip of the appendix according to Pathology Volume in Clinical Technical Operational Standards,a few scattered heteromorphic cell masses are found in the submucosa,muscular layer and serosa of the appendix.After sampling again,heteromorphic cell mass increase obviously,pathological diagnosis is appendiceal carcinoid with appendicitis.The morbidity of appendiceal carcinoid is low and the rate of missed diagnosis is high.Therefore,pathologists should pay attention to observe the general situation of the appendix when taking samples,and take more samples or even send all the thickened parts,and do not mechanically according to the Pathology Volume in Clinical Technical Operational Standards to take 3 pieces,read the film must be careful,not limited to low times,as far as possible to reduce missed diagnosis.

关 键 词：阑尾 类癌 病理 漏诊 

分 类 号：R735.36[医药卫生—肿瘤]