重复经颅磁刺激治疗早期特发性面神经麻痹的疗效观察  

Efficacy of repeated transcranial magnetic stimulation in the treatment of early idiopathic facial palsy

作　　者：杨轩[1] 黎鸣[1] 王韵喃[1] 林敏婷[1] YANG Xuan;LI Ming;WANG Yunnan;LIN Minting(Foshan Hospital of TCM,Guangdong,Foshan 528000,China)

机构地区：[1]广东省佛山市中医院,广东佛山528000

出　　处：《中国医药科学》2020年第9期209-211,共3页China Medicine And Pharmacy

基　　金：广东省佛山市医学科研立项课题(20190085)。

摘　　要：目的观察重复经颅磁刺激技术(rTMS)治疗早期特发性面神经麻痹(IFP)的效果。方法采用随机数字表法将本院2019年1~8月收治的60例IFP患者分为两组,A组给予基础治疗,B组除基础治疗外加以rTMS治疗。治疗4周后评价疗效。结果B组治疗后瞬目反射异常程度要低于A组,差异有统计学意义(P<0.05);B组面神经CMAP波幅下降百分比严重程度较A组低,差异有统计学意义(P<0.05);B组的瞬目反射中R1引出率百分比明显高于A组,差异有统计学意义(P<0.05);两组均无明显不良反应发生。结论重复经颅磁刺激技术对于早期IFP的治疗有很好的临床疗效,为IFP治疗提供新的治疗手段。Objective To observe the efficacy of repeated transcranial magnetic stimulation(rTMS)in the treatment of early idiopathic facial palsy(IFP).Methods Sixty patients with IFP received by our hospital from January to August 2019 were selected and divided into two groups as per random number table method.The group A was given basic therapy,while group B applied rTMS in addition to basic therapy.The efficacies were evaluated in 4 weeks after treatment.Results The anomaly degree of blink reflex of group B was lower than that of group B,with statistically significant difference(P<0.05).The CMAP amplitude decline(by percentage)degree of group B was lower than that group A,with statistically significant difference(P<0.05).The R1 elicitationrate(by percentage)of blink reflex of group B was significantly higher than that of group A,with statistically significant difference(P<0.05).Both groups did not present any significant adverse reaction.Conclusion Clinical efficacy of rTMS in the treatment of early IFP was great,providing new therapeutic mean for treating IFP.

关 键 词：重复经颅磁刺激 面神经麻痹 瞬目反射 肌电图 

分 类 号：R745[医药卫生—神经病学与精神病学]