后腹腔镜根治术对肾癌患者ACTH、Cor水平的影响  

The Effect of Retroperitoneal Laparoscopic Radical Operation on ACTH and Cor

作　　者：刘佳生[1] LIU Jia-sheng(Urology Department,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)

机构地区：[1]佳木斯市中心医院泌尿外科,黑龙江佳木斯154002

出　　处：《医学信息》2020年第10期124-125,共2页Journal of Medical Information

摘　　要：目的探讨后腹腔镜根治术对肾癌患者促肾上腺皮质激素(ACTH)、皮质醇(Cor)水平的影响。方法回顾性分析2018年4月~2019年5月我院收治的84例肾癌患者临床资料,依据手术方式分为对照组与观察组,每组42例。对照组行开放性肾癌根治术,观察组行后腹腔镜根治术,比较两组围术期指标(术中出血量、手术时间、首次下床活动时间及住院时间)、ACTH及Cor水平。结果观察组术中出血量、手术时间、首次下床活动时间及住院时间均短于对照组,差异有统计学意义(P<0.05);两组治疗5 d后ACTH与Cor水平均较术前升高,但观察组较对照组低[(55.47±10.03)g/ml vs (91.52±10.46)g/ml]、[(163.24±34.51)ng/ml vs (236.13±37.48)ng/ml],差异有统计学意义(P<0.05)。结论肾癌患者行后腹腔镜根治术治疗可减少术中出血量,缩短手术用时、首次下床活动时间及住院时间,降低ACTH、Cor水平。Objective To investigate the effect of retroperitoneal laparoscopic radical surgery on the levels of(ACTH) and Cortisol(Cor) in patients with renal cell carcinoma.Methods The clinical data of 84 kidney cancer patients admitted to our hospital from April 2018 to May 2019 were retrospectively analyzed, according to the operation method, it was divided into a control group and an observation group, with 21 patients in each.The control group underwent open radical nephrectomy, and the observation group underwent retroperitoneal laparoscopic radical resection. The perioperative indicators(intraoperative blood loss, operation time, first time out of bed and hospital stay), ACTH and Cor levels were compared between the two groups.Results The intraoperative blood loss, operation time, first time out of bed and hospitalization time of the observation group were shorter than that of the control group, the difference was statistically significant( P<0.05);After 5 d of treatment, the levels of ACTH and Cor in the two groups were higher than before surgery, but the observation group was lower than the control group [(55.47 ±10.03) g/ml vs(91.52±10.46) g/ml], [(163.24±34.51) ng/ml vs(236.13±37.48) ng/ml], the difference was statistically significant(P<0.05).Conclusion Laparoscopic radical surgery for patients with renal cell carcinoma can reduce intraoperative bleeding, shorten the operation time, the first time out of bed and the total hospital stay,and reduce ACTH and Cor levels.

关 键 词：肾癌 后腹腔镜根治术 促肾上腺皮质激素 皮质醇 

分 类 号：R737.11[医药卫生—肿瘤]