木村病17例临床病理分析  

Clinicopathological analysis of 17 cases of Kimura’s disease

作　　者：林楠 高宁[1] 蔡菁华[1] 许曼君 陈艳[1] 何巍[1] LIN Nan;GAO Ning;CAI Jinghua;XU Manjun;CHEN Yan;HE Wei(Department of Oral and Maxillofacial Surgery,The First Affiliated Hospital of Zhengzhou University,450052,China)

机构地区：[1]郑州大学第一附属医院口腔颌面外科,450052

出　　处：《实用口腔医学杂志》2020年第3期497-500,共4页Journal of Practical Stomatology

摘　　要：目的:分析木村病(Kimura’s Disease,KD)临床表现、病理变化及两者关系。方法:回顾性分析17例KD病例,并与国内外相关文献比较。结果:17例患者均为男性,多发生于头颈部及唾液腺;嗜酸性粒细胞绝对值、计数值及IgE补体定量测定偏高;镜下见病变累及唾液腺和淋巴结,形成淋巴滤泡和微脓肿;免疫组化相关抗体、核抗原Ki-67增殖指数也有特征性。结论:根据KD临床表现、实验室检查、病理学特点,辅以免疫组化,可进行早期诊断与治疗。Objective:To study the clinical manifestations,pathological changes and their relationship of Kimura’s Disease(KD).Methods:Data of 17 cases of KD were analyzed retrospectively and compared with those of related literature domestic and abroad.Results:17 patients were all male,most of the lesion were in head,neck and salivary gland;the absolute and count value of eosinophils and IgE complement quantity were on the high level.Microscopically,the lesions involved salivary gland and lymph nodes,forming lymph follicles and microabscesses.The expression of related antibodies and Ki-67 proliferation index were characteristic.Conclusion:Early diagnosis and treatment can be made according to the clinical manifestations,laboratory examination,pathological characteristics and immunohistochemistry of KD.

关 键 词：木村病(KD) 病理学 临床分析 

分 类 号：R739.8[医药卫生—肿瘤]