儿童结膜囊肿13例临床分析  

Clinical analysis of 13 children with conjunctival cyst

作　　者：白大勇[1] 苏学刚 崔燕辉[1] 张诚玥[1] 李莉[1] Bai Da-yong;Su Xue-gang;Cui Yan-hui(Department of Ophthalmology,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,China.)

机构地区：[1]首都医科大学附属北京儿童医院眼科,儿科学国家重点学科,国家儿童医学中心,100045 [2]北京儿童医院顺义妇幼保健院眼科

出　　处：《中国斜视与小儿眼科杂志》2020年第1期26-29,I0008,共5页Chinese Journal of Strabismus & Pediatric Ophthalmology

基　　金：北京市属医院科研培育计划项目(编号PX2019047)。

摘　　要：目的探讨儿童结膜囊肿患者的组织病理学分类和临床特点。方法对13例儿童结膜囊肿手术的患者回顾性分析,包括年龄、性别、眼部疾病、发病部位、手术情况、组织病理学性质等。结果13例眼部结膜囊肿患儿,平均年龄6.2岁,男9例,女4例;原发疾病分别为:先天性眼球震颤2例,共同性内斜视术后1例,间歇性外斜视术后4例,连续性外斜视3例,残余性外斜视1例,先天性囊肿1例,视网膜母细胞瘤眼摘术后继发囊肿1例。术后10例行病理检查,其中9例(90%)结膜上皮下血管组织增生,7例可见淋巴管增殖。2例可见囊肿与肌肉组织相连。9例结膜囊肿完整切除,4例术中破裂,2例复发。结论儿童结膜囊肿病因多因眼肌手术后结膜上皮碎片残留在结膜下,可伴有炎性细胞浸润,血管及淋巴管增生,术中剥除尽量行钝性分离,术中需要保护眼外肌和巩膜壁,囊肿破裂后容易复发。Objective To investigate the histopathological and clinical features of conjunctival cysts in children.Methods A retrospective analysis of 13 children with conjunctival cysts was performed,including age,gender,eye disease,lesion,surgery,and histopathology.Results Average age 6.2 years old in 13 patients with conjunctival cysts,9 males and 4 females.The primary diseases were congenital nystagmus in 2 cases,concomitant esotropia in 1 cases,intermittent exotropia in 4 cases,3 case of continuous exotropia,1 case of residual exotropia,1 case of congenital cyst,and 1 case of secondary cyst after eyeball removal of retinoblastoma.Pathological examination was performed in 10 cases after operation.Among them,9 cases(90%)had subepithelial vascular tissue hyperplasia,and 7 cases showed lymphatic proliferation.In 2 cases,cysts were adhered to muscle tissue.9 cases of conjunctival cysts were completely resected,4 cases were ruptured intraoperatively,and 2 cases relapsed.Conclusion The cause of conjunctival cyst in children is mostly due to the conjunctival epithelial debris remaining under the conjunctiva after ocular muscle surgery.It may be accompanied by inflammatory cell infiltration,vascular and lymphatic hyperplasia.Careful cyst removal should be carried out during surgery,and blunt separation should be performed as much as possible.Extraocular muscle and scleral wall should be protected during the surgery.The cyst is prone to recurrence after rupture.

关 键 词：结膜囊肿 儿童 病理 

分 类 号：R772.2[医药卫生—眼科]