血管超声对静脉溶栓疗效影响因素的研究  

Study on the influencing factors of thrombolytic effect with vascular ultrasound

作　　者：王军杰[1] 吕爱红[1] 李兆妍[1] WANG Junjie;LYU Aihong;LI Zhaoyan(The First People's Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第一人民医院,河南郑州450000

出　　处：《中国实用神经疾病杂志》2020年第8期706-710,共5页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析血管超声影像学特征与缺血性脑卒中静脉溶栓(IVT)治疗效果的相关性。方法IVT时对入组患者进行首次TCD检查,IVT 24 h内进行血管超声检查,探讨血管超声影像表现与静脉溶栓治疗后“显著改善”是否相关。结果在侧支循环、溃疡性斑块、房颤、右向左分流几个因素上,显著改善组和未显著改善组的差异有统计学意义(P<0.05),右向左分流和侧支循环建立是与“显著改善”相关的独立预测因素(P<0.05)。结论血管超声检查可以获得有价值的影像学和血流动力学信息,便于床旁操作、动态观察,可广泛应用于IVT诊疗过程中。Objective To analyze the relationship between the characteristics of vascular ultrasound and the effect of IVT in ischemic stroke.Methods First TCD examination was performed when IVT and vascular ultrasound examination was performed within 24 hours after IVT.The relationship between the characteristics of vascular ultrasound and"remarkable improvement"after intravenous thrombolysis was investigated.Results There were significant differences in collateral circulation,atrial fibrillation,ulcerative plaques and RLS between the two groups(P<0.05).Right-to-left shunt and collateral circulation were independent predictors of remarkable improvement after intravenous thrombolysis(P<0.05).Conclusion The vascular ultrasound examination can obtain valuable imaging and hemodynamic information,which is convenient for bedside operation and dynamic observation,and can be widely used in the diagnosis and treatment of IVT.

关 键 词：血管超声 缺血性脑卒中 静脉溶栓 TCD发泡试验 右向左分流 

分 类 号：R743.3[医药卫生—神经病学与精神病学]