鼻腔内翻性乳头状瘤病因学研究现状  

Research status in etiology of nasal inverted papilloma

作　　者：陈长康 杨国棠[1] 刘海宁 杨贵[1] Chen Changkang;Yang Guotang;Liu Haining;Yang Gui(Department of Otolaryngology,Shenzhen Longgang Central Hospital,Shenzhen 518172,China;Guangzhou Traditional of Chinese Medicine University Shenzhen Clinical Medical College,Shenzhen 518034,China)

机构地区：[1]深圳市龙岗中心医院耳鼻咽喉科,518172 [2]广州中医药大学深圳临床医学院,深圳518034

出　　处：《国际耳鼻咽喉头颈外科杂志》2020年第3期172-175,共4页International Journal of Otolaryngology-Head and Neck Surgery

摘　　要：鼻腔内翻性乳头状瘤是一种上皮细胞良性过度生长的病变,但其仍具有破坏性、复发性以及恶变趋向,严重危害人们健康,给社会造成极大负担。目前关于鼻腔内翻性乳头状瘤的发生,并没有完全阐明具有因果关系的病因。研究表明可能与病毒感染、慢性炎症、吸烟、环境因素、宿主基因等有关。随着生物技术的迅速发展,相关的研究也在不断进展。本文就关于近年鼻腔内翻性乳头状瘤在病毒感染、吸烟、慢性炎症、环境因素、宿主基因等方面的研究进展进行综述。Nasal inverted papilloma(NIP)is a kind of epithelial cell growth of benign lesions,but it's still destructive,recurrent malignant change and trend.At present,the cause of nasal inverted papilloma has not been fully elucidated.Studies have shown that it may be related to viral infection,chronic inflammation,smoking,environmental factors,host genes,etc.With the development of biotechnology,the related research has made a lot of progress.This article reviews the recent advances in the etiology of nasal invert papilloma in terms of viral infection,smoking,chronic inflammation,environmental factors,and host genes,etc.

关 键 词：鼻腔 乳头状瘤 内翻 

分 类 号：R739.62[医药卫生—肿瘤]