规则性肝段/肝叶切除术对复杂性肝内胆管结石患者结石清除率、并发症及复发率的影响  

Effect of Regular Hepatic Segment/Hepatic Lobectomy on Stone Clearance, Complications and Recurrence Rate in Patients with Complex Intrahepatic Cholelithiasis

作　　者：虞名旭 林型城 徐定银 孙广正 单云峰[2] Yu Mingxu;Lin Xingcheng;Xu Dingyin;Sun Guangzheng;Shan Yunfeng(The Third Affiliated Hospital of Wenzhou Medical University,Wenzhou 325200;The First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325006)

机构地区：[1]温州医科大学附属第三医院,温州325200 [2]温州医科大学附属第一医院,温州325006

出　　处：《数理医药学杂志》2020年第6期791-793,共3页Journal of Mathematical Medicine

摘　　要：目的:探究规则性肝段/肝叶切除术对复杂性肝内胆管结石患者结石清除率、并发症以及复发率的影响。方法:择取某院2018年1月~2019年1月期间收治的68例复杂性肝内胆管结石患者作为研究对象,随机数表划分为两组后应用不同的治疗方案。实验组34例患者接受规则性肝段/肝叶切除术,而对照组34例患者接受不规则形肝段/肝叶切除术,比较两组患者临床疗效。结果:(1)结石清除率:实验组患者结石清除率为94.12%,显著高于对照组患者,两组间差异有统计学意义(P<0.05);(2)并发症发生率:实验组患者术后并发症发生率为11.76%,显著低于对照组患者,组间差异具备统计学意义(P<0.05);(3)复发率:对两组患者进行为期1年的随访,发现实验组患者结石复发率仅为2.94%,明显低于对照组患者,组间差异具备统计学意义(P<0.05)。结论:应用规则性肝段/肝叶切除术用于治疗复杂性肝内胆管结石疾病,在结石清除率、术后并发症以及复发率方面均优于不规则形肝段/肝叶切除术,临床疗效较好,具有借鉴意义。Objective:To explore the effect of regular hepatic segment/hepatic lobectomy on stone clearance, complications and recurrence rate in patients with complex intrahepatic cholelithiasis.Methods:68 patients with complex intrahepatic cholelithiasis treated in a hospital from January 2018 to January 2019 were selected as the study objects and divided into two groups according to the randomized table,and then the different treatment schemes were applied.34 patients in the experimental group received regular hepatectomy,while the other 34 patients in the control group received irregular hepatectomy.The clinical efficacy of two groups were compared.Results:(1)The stone removal rate of the experimental group was 94.12%,which was significantly higher than that of the control group,and the difference between the two groups was statistically significant(P<0.05).Among the patients in the experimental group,the incidence of postoperative complications was 11.76%,which was significantly lower than that in the control group(P<0.05).After one-year follow-up,it was found that the stone recurrence rate in the experimental group was only 2.94%,which was significantly lower than that in the control group(P<0.05).Conclusion:Regular hepatectomy is superior to irregular hepatectomy in stone removal rate,postoperative complications and recurrence rate in the treatment of complex intrahepatic cholelithiasis,which has good clinical effect and reference significance.

关 键 词：规则性肝段/肝叶切除术 复杂性肝内胆管结石 结石清除率 并发症 复发率 

分 类 号：R575.7[医药卫生—消化系统]