经手术治疗宫颈癌患者的临床特征研究  

Clinical Features of Patients with Cervical Cancer Treated by Surgery

作　　者：张涛红 张萌 高丽 薛艳[1] 王丽莎[1] 安瑞芳[1] ZHANG Taohong;ZHANG Meng;GAO Li;XUE Yan;WANG Lisha;AN Ruifang(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Office of Medical Information Management,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]西安交通大学第一附属医院妇产科,陕西省西安市710061 [2]西安交通大学第一附属医院医疗信息管理办公室,陕西省西安市710061

出　　处：《中国全科医学》2020年第25期3207-3211,共5页Chinese General Practice

摘　　要：背景宫颈癌是威胁女性健康的生殖道恶性肿瘤之一,目前有开腹、腹腔镜及机器人等手术治疗方式。既往研究多针对各种手术治疗的有效性和安全性,以及人乳头瘤病毒(HPV)感染类型及高危因素,但对于经手术治疗的宫颈癌患者临床特征研究较少。目的探讨经手术治疗宫颈癌患者的临床表现及特点。方法收集2013年1月-2017年12月在西安交通大学第一附属医院确诊为宫颈癌并经手术治疗的776例住院患者,比较不同年龄、户籍所在地及血型患者的结婚年龄、孕次、产次、初潮年龄、初产年龄、就诊原因、临床分期及病理组织类型等临床特征。结果 776例宫颈癌手术患者的平均年龄为(59.8±9.8)岁,64.4%(500/776)为本省外市,88.5%(687/776)为鳞癌,7.3%(57/776)为腺癌,余为宫颈腺鳞癌及其他特殊病理类型(小细胞癌、神经内分泌癌等)。≤35、36~49、≥50岁患者孕次、产次、初潮年龄、初产年龄、就诊原因、临床分期、病理组织类型比较,差异有统计学意义(P<0.05);结婚年龄、分化程度、肌层浸润深度、脉管浸润及盆腔淋巴结转移比较,差异无统计学意义(P>0.05);本省市、本省外市、外省市患者结婚年龄、产次、初潮年龄及初产年龄比较,差异有统计学意义(P<0.05);孕次、就诊原因、临床分期、病理组织类型、分化程度、肌层浸润深度、脉管浸润及盆腔淋巴结转移比较,差异无统计学意义(P>0.05);不同血型患者孕次比较,差异有统计学意义(P<0.05),其余临床病理因素比较,差异无统计学意义(P>0.05)。结论经手术治疗的宫颈癌患者仍以鳞癌为主,多为中老年人,且本省外市患者居多。另外,宫颈癌的发生发展可能与血型及地区分布无关,但与年龄相关,故应加强本地区及周边地区中老年人的宫颈癌筛查。Background Cervical cancer is one of the malignant tumors of the reproductive tract that threaten women's health.Currently,there are different surgical treatments such as laparotomy,laparoscopy and robot assisted surgery.Previous studies have focused on the effectiveness and safety of various surgical treatments,as well as the types of human papillomavirus(HPV)infection and high-risk factors,but the clinical characteristics of patients with cervical cancer treated by surgery in this area have not been analyzed.Objective To investigate the clinical manifestations and characteristics of patients with cervical cancer treated by surgery.Methods The Data of 776 inpatients who were diagnosed with cervical cancer and surgically treated in the First Affiliated Hospital of Xi'an Jiaotong University from January 2013 to December 2017 were collected.To compare the clinical characteristics of the patients with different age,the place of residence and the blood type.The clinical characteristics of patients in different groups such as marriage age,gravidity,parity,menarche age,primiparity age,reasons for visiting,clinical stages and histopathological types were analyzed.Results The average age of 776 cervical cancer patients was(59.8±9.8)years old,64.4%(500/776)of them were from other cities,88.5%(687/776)of them were squamous carcinoma,7.3%(57/776)of them were adenocarcinoma,the rest were adenocarcinoma and other special pathological type(s small cell carcinoma,neuroendocrine carcinoma,etc.).There were significant differences in the gravidity,parity,menarche age,primiparity age,reasons for visiting,clinical stages and histopathological types among patients aged≤35,36-49 and≥50 years(P<0.05),but the marriage age,differentiation of tumor cells,myometrial invasion,vascular invasion and pelvic lymph node metastasis had no statistical significance(P>0.05).There were significant differences in the marriage age,parity,menarche age,and primiparity age among patients in this province,cities outside the province,and other province

关 键 词：宫颈肿瘤 妇科外科手术 临床特征 

分 类 号：R737.33[医药卫生—肿瘤]