生大黄联合低剂量复方聚乙二醇电解质散清洁肠道的临床效果  

Clinical effect of rhubarb combined with low-dose PGEP on intestinal cleaning

作　　者：李帆 闫华楠 张宏伟 郭永泽[2] LI Fan;YAN Huanan;ZHANG Hongwei;GUO Yongze(School of Clinical Medicine,Hebei University of Engineering,Handan 056002,Hebei,China;Gastroenterology Department of Affiliated Hospital,Hebei University of Engineering,Handan 056002,Hebei,China)

机构地区：[1]河北工程大学临床医学院,河北邯郸056002 [2]河北工程大学附属医院消化内科,河北邯郸056002

出　　处：《右江医学》2020年第5期357-362,共6页Chinese Youjiang Medical Journal

摘　　要：目的探讨生大黄联合低剂量复方聚乙二醇电解质散(PGEP)溶液清洁肠道的效果,观察生大黄在降低费用的同时,是否可以保证肠道清洁度,减少不良反应发生率,是否优于单纯口服PGEP溶液。方法选取就诊于河北工程大学附属医院进行肠镜检查的患者123例,随机分为A、B两组,A组64例,B组59例,肠道准备方法:A组仅用PGEP,B组用3 g生大黄+低剂量PGEP,比较两组患者肠道清洁度、肠道气泡含量及可视程度、耐受性等评分和不良反应、夜间睡眠情况。结果两组肠道气泡含量及可视程度评分、不适程度评分、睡眠时长差异无统计学意义(P>0.05)。A组全结肠液体评分、渥太华肠道准备量表(OBPS)评分、耐受评分均高于B组(P<0.05)。两组患者恶心程度、腹胀程度、夜间苏醒次数比较,A组均多于B组(P<0.05)。结论肠镜检查前使用生大黄联合低剂量PGEP进行肠道准备,可明显提高肠道清洁质量,减少结肠镜检查前的不良反应,提高患者耐受程度,且明显提高患者夜间睡眠的连续性,是一种安全、有效的肠道准备方案。Objective To explore the effect of rhubarb combined with low-dose polyethylene glycol electrolyte powder(PGEP)on intestinal cleaning,and to observe whether rhubarb can ensure intestinal cleanliness and reduce the incidence of adverse reactions while reducing costs,and whether it is superior to PGEP solution alone.Methods A total of 123 patients who underwent colonoscopy in the Affiliated Hospital of Hebei University of Engineering were selected and included in this study.They were randomly divided into two groups:group A(64 cases)and group B(59 cases).Intestinal preparation methods:patients in the group A were only treated with PGEP,and patients in the group B were treated with rhubarb(3 g)+low-dose PGEP.And then,intestinal cleanliness scores,intestinal bubble volume and visual degree,tolerance and adverse reactions,and nocturnal sleep of patients were compared between the two groups.Results There was no statistically significant difference in intestinal bubble volume,visual degree,discomfort score and sleep duration between the two groups(P>0.05).The total colonic fluid score,Ottawa bowel preparation scale(OBPS)score and tolerance score in the group A were higher than those in the group B(P<0.05).The degree of nausea and abdominal distention of the group A was more severe than that of the group B,and the times of waking up at night were more in the group A than in the group B(P<0.05).Conclusion Before colonoscopy,rhubarb combined with low-dose PGEP can significantly improve the quality of intestinal cleaning,reduce adverse reactions,improve the tolerance of patients,and significantly improve the continuity of sleep at night,which is a safe and effective solution for intestinal preparation.

关 键 词：肠道准备 结肠镜检查 大黄 复方聚乙二醇电解质散 

分 类 号：R574.6[医药卫生—消化系统]