正确认识保留关节的保肢术在治疗肢体恶性骨肿瘤中的价值  

Joint-preservation limb salvage in the treatment of limb malignant bone tumors

作　　者：于秀淳 YU Xiu-chun(Department of Orthopedics,PLA 960 the Hospital,Jinan,Shandong,250031,China)

机构地区：[1]解放军九六〇医院骨科,济南250031

出　　处：《中国骨与关节杂志》2020年第5期321-323,共3页Chinese Journal of Bone and Joint

摘　　要：以骨肉瘤为代表的肢体恶性骨肿瘤,近年来随着各种治疗的发展与临床应用,患者的5年生存率由单纯截肢术时的不足20%提高至目前的60%~70%,同时保肢手术的成功率已达80%~90%[1-2]。随着生存期的延长,患者对提高生存质量的要求也越来越高。因此,如何在提高患者生存率的同时最大限度地保留肢体功能及外观已成为人们关注的焦点。Joint-preservation limb salvage of malignant bone tumors was first used as epiphysis-preservation in children,which was named along with different ages and epiphyseal plate closure.It aims to improve the satisfaction rate by keeping the integrity of the joint structure as much as possible after sufficient tumor removal following clear MRI tumor invasion range confirmation,further improving the post-operative limb functions on the premise of not increasing the occurrence of life-threatening complications,and avoiding the unequal length of bilateral limbs of children.It is mainly applicable to diaphysis or metaphysis malignant bone tumors in children that the epiphyseal plate has yet not been closed.It was found that the overall survival rate and MSTS score were not significantly reduced,the postoperative recurrence rate was lower,and the complications were not significantly increased after a retrospective analysis of the clinical data reported in the literature and comparison with tumor prosthesis replacement.Therefore,joint-preservation limb salvage is feasible and effective in the treatment of malignant bone tumors with higher satisfaction rate.

关 键 词：骨肿瘤 保肢 修复外科手术 肢体 

分 类 号：R738.1[医药卫生—肿瘤]