微创肺叶切除术和微创肺段切除术治疗非小细胞肺癌的效果对比  

Comparison of the Therapeutic Effects of Minimally Invasive Lobectomy and Minimally Invasive Segmentectomy in Patients with Non-small Cell Lung Cancer

作　　者：叶志彬[1] 陈小聪[1] 陈国标[1] 李伟阳[1] 周建平[1] YE Zhibin;CHEN Xiaocong;CHEN Guobiao(Dongguan People's Hospital,Dongguan,523059)

机构地区：[1]广东省东莞市人民医院,523059

出　　处：《实用癌症杂志》2020年第6期963-966,974,共5页The Practical Journal of Cancer

摘　　要：目的探讨微创肺叶切除术和微创肺段切除术治疗非小细胞肺癌的效果差异。方法选择东莞市人民医院完成肺癌手术的患者60例的资料进行回顾性研究,根据患者的治疗方法将患者分为A组(n=30)与B组(n=30)。A组使用微创肺叶切除手术,B组使用微创肺段切除手术。对比2组的治疗效果。结果B组的手术耗时多于A组,B组的胸腔管引流量、胸腔管引流时间、术后住院时间低于A组(t=-2.763,2.828,2.958,2.016,P<0.05),2组的失血量、术中清扫淋巴结数量差异不具有统计学意义(t=-1.946,0.265,P>0.05)。经过手术后,2组的FVC,FEV1%均降低,B组的降低幅度小于A组(t=-9.668,-5.264,P<0.05)。手术后2组患者的C反应蛋白浓度均增高,在术后1 d和术后5 d的对比中,均为B组的血清C反应蛋白低于A组(t=7.848,4.069,P<0.05)。2组各类术后并发症的发生率差异均不具有统计学意义(χ^2=0.000,0.268,0.000,0.480,P>0.05)。结论采用微创肺段切除术治疗早期非小细胞肺癌,可以取得良好的近期治疗效果,有助于患者的康复,但尚需要大样本量的研究进行深入探讨。Objective To explore the difference in therapeutic effect between minimally invasive lobectomy and minimally invasive segmental resection in patients with non-small cell lung cancer.Methods A retrospective study was performed on 60 patients who completed lung cancer surgery.Patients were divided into group A(n=30)and group B(n=30)according to the patient's treatment.Group A was treated with minimally invasive lobectomy,and group B was treated with minimally invasive lung segmentectomy.Compare the therapeutic effects of the 2 groups.Results The operation time of group B was more than that of group A.The drainage of thoracic tube and the drainage time of thoracic tube in group B were lower than those in group A(t=-2.763,2.828,2.958,2.016,P<0.05).There was no significant difference in the amount of blood loss between the 2 groups and the number of lymph nodes removed during the operation(t=-1.946,0.265,P>0.05).After surgery,the FVC and FEV1%of the 2 groups were decreased,and the decrease of the B group was smaller than that of the A group(t=-9.668,-5.664,P<0.05).The C-reactive protein concentration of the 2 groups increased after surgery.The serum C-reactive protein in group B was lower than that of group A at 1 day after surgery and 5 days after surgery(t=7.848,4.069,P<0.05).There were no statistically significant differences in data between the 2 groups(χ^2=0.000,0.268,0.000,0.480,P>0.05).Conclusion Minimally invasive segmentectomy for patients with early stage non-small cell lung cancer can achieve good short-term treatment and help patients recover.However,a large sample size study is needed for further study.

关 键 词：肺叶切除术 肺段切除术 非小细胞肺癌 淋巴结 

分 类 号：R734.2[医药卫生—肿瘤]