急性呼吸系统疾病营养支持疗法指南的系统评价  

Guidelines on Nutrition Support Therapy for Acute Respiratory Disease:A Systematic Review

作　　者：李潇潇[1,3,4] 刘芳 葛庆岗[2] 赵彬 于康[6] 张昕怡[3] 李超[2] 史录文 赵荣生 LI Xiao-xiao;LIU Fang;GE Qing-gang;ZHAO Bin;YU Kang;ZHANG Xin-yi;LI Chao;SHI Lu-wen;ZHAO Rong-sheng(Department of Pharmacy,Peking University Third Hospital,Beijing 100191,China;Critical Care Medicine Department,Peking University Third Hospital,Beijing 100191,China;Department of Pharmacy Administration and Clinical Pharmacy,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China;Institute for Drug Evaluation,Peking University Health Science Center,Beijing 100191,China;Department of Pharmacy,Peking Union Medical College Hospital,Beijing 100730,China;Department of Clinical nutrition,Peking Union Medical College Hospital,Beijing 100730,China)

机构地区：[1]北京大学第三医院药剂科,北京100191 [2]北京大学第三医院危重医学科,北京100191 [3]北京大学药学院药事管理与临床药学系,北京100191 [4]北京大学医学部药物评价中心,北京100191 [5]北京协和医院,药剂科,北京100730 [6]北京协和医院临床营养科,北京100730

出　　处：《中国药学杂志》2020年第9期671-678,共8页Chinese Pharmaceutical Journal

基　　金：国家科技重大专项课题资助(2017ZX09304012-008)。

摘　　要：目的系统评价营养支持疗法(简称“营养支持”)在急性呼吸系统疾病应用的临床指南,以期为新型冠状病毒肺炎(COVID-19)等冠状病毒感染的营养支持提供循证参考。方法计算机检索Pubmed、EMBASE、CNKI等数据库,全球主要营养学会网站、指南网站。纳入急性呼吸系统疾病营养支持指南,提取资料并进行质量评价,列出主要推荐意见。结果最终纳入10篇指南,制定时间为2006~2019年。指南质量为A级6篇,B级3篇,C级1篇。在指南研究与评价工具(AGREE)Ⅱ涉及各领域中,范围与目的、清晰性、独立性的总分最高,应用性普遍得分较低。各指南侧重点不同,可互为补充,对同一问题的推荐意见基本一致。结论COVID-19营养支持策略可遵循既往在重症、急性呼吸窘迫综合征、肺炎等发表的高质量指南推荐意见。OBJECTIVE To systematically review the related guidelines of nutrition support therapy(hereinafter referred to as nutrition support)in acute respiratory disease,and to provide evidence-based evidences for clinical nutrition in coronavirus disease 2019(COVID-19).METHODS Retrieved from PubMed,EMBase,CNKI,etc.,websites of association in nutrition and global guideline databases.The guidelines in nutrition support for related diseases were collected.Recommendations were summarized after data extraction and quality evaluation.RESULTS A total of 10 guidelines were enrolled,with development time ranging from 2006 to 2019.There were 6 guidelines with quality of level A,3 with level B,and 1 with level C.“scope and purpose”,“clarity”and“independence”showed the higher scores in AGREEⅡ,and“applicability”showed generally low scores.There were differences among emphases of guidelines,however,supplements for each other,and the recommendations for the same questions showed substantial agreement.CONCLUSION The recommendations,in high quality guidelines of critical illness,acute respiratory distress syndrome,pneumonia,etc.,could be applied to nutrition support in COVID-19.

关 键 词：急性呼吸系统疾病 营养支持 指南评价工具 系统评价 循证 

分 类 号：R969.3[医药卫生—药理学]