Can adiponectin have an additional effect on the regulation of food intake by inducing gastric motor changes?  

作　　者：Eglantina Idrizaj Rachele Garella Roberta Squecco Maria Caterina Baccari 

机构地区：[1]Department of Experimental and Clinical Medicine,Section of Physiological Sciences,University of Florence,Florence 50134,Italy

出　　处：《World Journal of Gastroenterology》2020年第20期2472-2478,共7页世界胃肠病学杂志（英文版）

基　　金：Supported by the CRF Foundation,No.2017.0777。

摘　　要：The regulation of food intake is a complex mechanism,and the hypothalamus is the main central structure implicated.In particular,the arcuate nucleus appears to be the most critical area in the integration of multiple peripheral signals.Among these signals,those originating from the white adipose tissue and the gastrointestinal tract are known to be involved in the regulation of food intake.The present paper focuses on adiponectin,an adipokine secreted by white adipose tissue,which is reported to have a role in the control of feeding by acting centrally.The recent observation that adiponectin is also able to influence gastric motility raises the question of whether this action represents an additional peripheral mechanism that concurs with the central effects of the hormone on food intake.This possibility,which represents an emerging aspect correlating the central and peripheral effects of adiponectin in the hunger-satiety cycle,is discussed in the present paper.

关 键 词：ADIPOKINES ADIPONECTIN Adipose tissue Food intake Gastric motility Satiety signals 

分 类 号：R333[医药卫生—人体生理学]