Gastric pyloric gland adenoma resembling a submucosal tumor:A case report  

作　　者：Cong-Cong Min Jun Wu Feng Hou Tao Mao Xiao-Yu Li Xue-Li Ding Hua Liu 

机构地区：[1]Department of Gastroenterology,The Affiliated Hospital of Qingdao University,Qingdao 266003,Shandong Province,China [2]Department of Pathology,The Affiliated Hospital of Qingdao University,Qingdao 266003,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2020年第11期2380-2386,共7页世界临床病例杂志

基　　金：Supported by the National Natural Science Foundation of China,No.81802777;Key Research and Development Plan of Shandong Province,No.2018GSF118214;China Postdoctoral Science Foundation,No.2017M612221.

摘　　要：BACKGROUND Pyloric gland adenoma(PGA)is a recently described and rare tumor.Submucosal tumor(SMT)-like PGA is more difficult to diagnose and differentiate from other submucosal lesions.CASE SUMMARY We present the case of a 69-year-old man with a 10 mm SMT-like elevated lesion with an opening in the upper part of the gastric body,referred to our hospital for further endoscopic treatment.Magnifying endoscopy with narrow-band imaging,endoscopic ultrasonography,and complete endoscopic submucosal dissection were performed on the patient.Histopathological findings revealed tightly packed tubular glands lined with cuboidal or columnar cells that had round-tooval nuclei containing occasional prominent nucleoli and an eosinophilic cytoplasm similar to that in non-neoplastic gastric pyloric glands.Additionally,immunohistochemical analysis showed positive staining for both mucin 5AC and mucin 6.Therefore,we arrived at the final diagnosis of gastric PGA.Although there was no apparent malignant component in this tumor,PGA has been considered a precancerous disease with a high risk of transformation into adenocarcinoma.CONCLUSION PGA should be considered when detecting gastric SMT-like lesions.Physicians and pathologists should focus on PGA due to its malignant potential.

关 键 词：Pyloric gland adenoma Submucosal tumor Endoscopic submucosal dissection Case report 

分 类 号：R735.2[医药卫生—肿瘤]