采用ESPEN营养不良诊断标准评价两种营养筛查工具在肿瘤住院患者中的有效性  

Validity Evaluation of Two Screening Tools in Hospitalized Cancer Patients by ESPEN Criteria

作　　者：周虹[1] 黄艳红 林燕芳[1] 林志航[1] 林志强[1] Zhou Hong;Huang Yanhong;Lin Yanfang;Lin Zhihang;Lin Zhiqiang(Department of Pharmacy,the First Hospital of Quanzhou Affiliated to Fujian Medical University,Fujian Quanzhou 362000,China;Department of Oncology,the First Hospital of Quanzhou Affiliated to Fujian Medical University,Fujian Quanzhou 362000,China)

机构地区：[1]福建医科大学附属泉州第一医院药剂科,福建泉州362000 [2]福建医科大学附属泉州第一医院肿瘤内科,福建泉州362000

出　　处：《中国药师》2020年第5期884-886,共3页China Pharmacist

基　　金：福建省卫生计生青年科研课题(编号:2016-02-46)。

摘　　要：目的:采用欧洲临床营养和代谢学会(ESPEN)制定的营养不良诊断标准评定患者自评主观全面评定(PG-SGA)和营养风险筛查(NRS2002)用于肿瘤住院患者的有效性。方法:选取2018年7~11月肿瘤住院患者,分别采用NRS2002和PG-SGA进行营养筛查或评定,然后将结果与ESPEN营养不良诊断标准进行比较。结果:共466例患者纳入本研究,根据ESPEN营养不良诊断标准,25.3%的患者存在营养不良。PG-SGA筛查结果为35.6%的患者营养不良,NRS2002筛查结果为43.1%的患者有营养风险。PG-SGA和NRS2002的灵敏度分别为94.9%和93.2%,特异度分别为84.5%和73.9%;与ESPEN营养不良诊断标准的相关性,kappa值分别为0.700和0.544,ROC曲线下面积分别为0.941和0.864。结论:PG-SGA和NRS2002两种筛查工具与ESPEN营养不良标准相关性均较好,灵敏度高,NRS2002更便捷省时,更方便肿瘤住院患者营养不良筛查。Objective:To verify the accuracy of two most commonly used screening tools by comparing their findings by the new ESPEN criteria.Methods:Nutritional screening was performed in 466 patients on admission to hospitals from July to November 2018 with two nutritional screening tools:Nutritional Risk Screening 2002(NRS2002)and Patient-generated Subjective Global Assessment(PG-SGA).The screening results were then compared to the new ESPEN diagnostic criteria for malnutrition.Results:According to the ESPEN diagnostic criteria,25.3%of the patients were classified as malnourished.According to the result of PG-SGA,35.6%of the patients were undernourished,and according to the result of NRS2002,43.1%of the patients were found to be at moderate/high risk of malnutrition.The sensitivity of PG-SGA and NRS2002 was 94.9%and 93.2%,and the specificity was 84.5%and 73.9%,respectively.PG-SGA was found to be better correlated with the ESPEN diagnostic criteria(κ=0.700,P<0.001)as compared to NRS2002(κ=0.544,P<0.001).ROC area under the curve of PG-SGA and NRS2002 was 0.941 and 0.864,respectively.Conclusion:According to our results,both screening tools are well correlated with the ESPEN criteria for the definition of malnutrition,while NRS2002 is easier to operate with shorter time,therefore,NRS2002 can identify the malnourished cancer patients more conveniently.

关 键 词：营养风险筛查2002 患者自评主观全面评定 营养风险 营养不良 

分 类 号：R73[医药卫生—肿瘤]