浅谈老年患者消化系疾病的临床特点及质子泵抑制剂联合用药的研究  

Studys on the clinical characteristics of digestive diseases in elderly patients and combined drug use with proton pump inhibitor

作　　者：何恰恰 He Qiaqia(Department of Doctor and Nurse,Shandong QingdaoWelfare Institution,Qingdao,Shandong,266200,China)

机构地区：[1]山东省青岛市社会福利院医护科,山东青岛266200

出　　处：《当代医学》2020年第17期22-25,共4页Contemporary Medicine

摘　　要：目的探讨老年患者消化系统疾病的临床特点及合理用药方案。方法选择2012年1月至2018年1月本院收治的82例老年患者消化系疾病患者,随机分为观察组和对照组,每组41例。对照组患者按病情常规治疗,观察组在对照组基础上增加质子泵抑制剂治疗,对比分析两组患者临床治疗情况、康复速度、生活质量、复发率及用药安全性。结果观察组老年消化系疾病治疗总有效率为92.68%,显著高于对照组的82.93%,差异有统计学意义(P<0.05)。观察组患者消化系统症状改善时间(14.94±3.07)d、症状消失时间(27.79±6.01)d显著短于对照组的(21.34±1.26)d、(37.75±5.24)d,差异具有统计学意义(P<0.05)。观察组疗程结束后患者物质生活评分(23.15±2.03)分、躯体功能(22.06±2.07)分、心理功能评分(21.56±2.14)分、社会功能评分(23.85±1.05)分均显著高于对照组(19.65±2.59)分、(18.71±3.49)分、(18.12±1.34)分、(19.54±3.42)分,观察组生活质量总评分(88.53±10.12)分也显著高于对照组(77.18±10.24)分,差异具有统计学意义(P<0.05)。随访6~12个月,观察组复发率为9.76%,显著低于对照组的14.63%,差异有统计学意义(P<0.05)。观察组不良反应发生率为7.32%,低于对照组的17.07%,差异有统计学意义(P<0.05)。结论老年患者消化系疾病多为慢性病程,预后较差,可在常规治疗基础上联用质子泵抑制剂,进一步提升临床疗效,改善患者预后和生活质量,降低复发风险。Objective To investigate the clinical characteristics of digestive system diseases and rational drug use in elderly patients.Methods 82 elderly patients with digestive diseases admitted to our hospital from January 2012 to January 2018 were randomly divided into observation group and control group,with 41 cases in each group.Patients in the control group received conventional treatment according to their condition,and patients in the observation group received proton pump inhibitor treatment on the basis of the control group.Clinical treatment,recovery speed,quality of life,recurrence rate and medication safety of patients in the two groups were compared and analyzed.Results The total treatment efficiency of digestive system diseases in the observation group(92.68%)was significantly higher than that in the control group(82.93%),and the difference was statistically significant(P<0.05).The improvement time of digestive symptoms in the observation group(14.94±3.07)d and the time of symptom disappearance(27.79±6.01)d were significantly lower than those in the control group(21.34±1.26)d and(37.75±5.24)d,with statistically significant difference(P<0.05).After the treatment,the physical life,physical function,psychological function and social function scores of the patients in the observation group[(23.15±2.03)scores,(22.06±2.07)scores,(21.56±2.14)scores,(23.85±1.05)scores]were significantly higher than those in the control group[(19.65±2.59)scores,(18.71±3.49)scores,(18.12±1.34)scores and(19.54±3.42)scores].The total score of life quality of the observation group(88.53±10.12)scores was also significantly higher than that of the control group(77.18±10.24)scores,and the difference was statistically significant(P<0.05).The follow-up period ranged from 6 to 12 months,and the recurrence rate of the observation group(9.76%)was significantly lower than that of the control group(14.63%),and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group(7.32%)was s

关 键 词：老年 消化系疾病 临床特点 合理用药 质子泵抑制剂 复发 

分 类 号：R57[医药卫生—消化系统]