组织型纤溶酶原激活剂在黄斑下出血治疗中的应用  

Application of tissue plasminogen activator in the treatment of submacular hemorrhage

作　　者：安广琪 金学民[2] 戴方方 李爽爽 韩金凤 李梦迪 雷博 An Guangqi;Jin Xuemin;Dai Fangfang;Li Shuangshuang;Han Jinfeng;Li Mengdi;Lei Bo(Department of Ophthalmology,People’s Hospital of Zhengzhou University,Henan Eye Hospital,Henan Eye Institute,Zhengzhou 450003,China;Department of Ophthalmology,The First Affiliated Hospital of Zhengzhou University,Henan Province Ophthalmic Hospital,Zhengzhou 450052,China)

机构地区：[1]郑州大学人民医院眼科,河南省立眼科医院,河南眼科研究所,郑州450003 [2]郑州大学第一附属医院眼科,河南省眼科医院,郑州450052

出　　处：《中华眼外伤职业眼病杂志》2020年第3期237-240,共4页Chinese Journal of Ocular Trauma and Occupational Eye Disease

基　　金：河南省科技厅项目(162102410004)。

摘　　要：黄斑下出血是一种极大影响患者视力预后的眼底病变,目前尚无标准化治疗方案。组织型纤溶酶原激活剂(tPA)在其治疗中起到重要的作用。本文旨在阐述黄斑下出血的病理生理机制、目前手术治疗手段。tPA在黄斑下出血治疗中的应用,并阐述其有效性及安全性;对比新旧两种药物及介绍新手术方式,以期对黄斑下出血的治疗提供一定的参考。Submacular hemorrhage is a kind of fundus disease that greatly affects the visual prognosis of patients.At present,there is no standardized treatment scheme.Tissue plasminogen activator(tPA)plays an important role in the treatment.The purpose of this paper is to elucidate the pathophysiological mechanism and the current surgical treatment methods and the application of tPA in the treatment of submacular hemorrhage.The efficacy of the old and new drugs is compared,and the new surgical methods are introduced,in order to provide some reference for the treatment of submacular hemorrhage.

关 键 词：出血 黄斑下 激活剂 纤溶酶原 组织型 

分 类 号：R77[医药卫生—眼科]