癌性疼痛规范化诊疗中临床药师的药学监护作用  

The Pharmacological Monitoring Function of Clinical Pharmacists in the Standardized Diagnosis and Treatment of Cancer Pain

作　　者：董明伟 DONG Ming-wei(Department of Pharmacy,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)

机构地区：[1]佳木斯市中心医院药剂科,黑龙江佳木斯154002

出　　处：《医学信息》2020年第11期151-153,共3页Journal of Medical Information

摘　　要：目的研究癌性疼痛规范化诊疗中临床药师的药学监护作用。方法选取2018年6月~2019年6月在我院诊治的124例癌性疼痛患者为研究对象,采用随机数字表法分为对照组和观察组,各62例。对照组采用常规治疗,观察组在对照组基础上给予临床药师药学监护干预,比较两组临床疼痛缓解率、治疗前后疼痛度评分、爆发痛次数、临床行为(遵医嘱用药、合理饮食、情绪稳定、坚持治疗)依从评分、不良反应(恶心、呕吐、腹泻、便秘、手脚麻木)缓解情况。结果观察组临床缓解率为83.87%,高于对照组的70.96%,差异有统计学意义(P<0.05);治疗后两组疼痛评分、爆发痛次数均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后观察组遵医嘱用药、合理饮食、情绪稳定依从评分均高于对照组,差异有统计学意义(P<0.05);干预后观察组不良反应缓解率高于对照组,差异有统计学意义(P<0.05)。结论癌性疼痛规范化诊疗中实施临床药师药学监护干预有助于提高癌性疼痛缓解率,降低疼痛评分,减少爆发痛次数,进一步提高患者临床诊治行为依从性和不良反应缓解率。Objective To study the pharmacological monitoring function of clinical pharmacists in the standardized diagnosis and treatment of cancer pain.Methods A total of 124 patients with cancer pain diagnosed and treated in our hospital from June 2018 to June 2019 were selected as the research object,using the random number table method to divide into control group and observation group,with 62 cases in each group.The control group was treated with conventional treatment,and the observation group was given a clinicarl pharmacist intervention on the basis of the control group,compared the clinical pain remission rate,pain score before and after treatment,number of outbreaks of pain,compliance score of clinical behavior(taking medicine according to doctor's advice,rational diet,emotional stability,and persistent treatment),and relief of adverse reactions(nausea,vomiting,diarrhea,constipation,and numbness of hands and feet)between the two groups.Results The clinical remission rate of the observation group was 83.87%,which was higher than that of the control group 70.96%,the difference was statistically significant(P<0.05);after treatment,the pain score and the number of outbreak pain in both groups were lower than before treatment,and the observation group the control group,the difference was statistically significant(P<0.05);after treatment,the observation group followed the doctor's instructions for medication,reasonable diet,and emotional stability compliance scores were higher than the control group,the difference was statistically significant(P<0.05);the observation group after intervention remission rate of adverse reactions was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion The implementation of clinical pharmacist pharmacological monitoring interventions in the standardized diagnosis and treatment of cancer pain can improve the cancer pain relief rate,reduce the pain score,reduce the number of outbreak pain,and further improve the patient's clinical compliance a

关 键 词：癌性疼痛 规范化诊疗 临床药师 药学监护 

分 类 号：R730.5[医药卫生—肿瘤]