安徽省144例新型冠状病毒肺炎患者中医证候特征  

Investigation and Analysis of Traditional Chinese Medicine Syndromes with 144 Cases of COVID-19 Patients in Anhui Province

作　　者：周静 陈晶晶 张念志[2] 朱笑笑 李晶 汪诗清 李允栋 韩明向[2] 陈炜[2] 董梅[2] 刘玲[2] 侯浩彬 丁震 刘新矿 姚莉[6] ZHOU Jing;CHEN Jing-jing;ZHANG Nian-zhi;ZHU Xiao-xiao;LI Jing;WANG Shi-qing;LI Yun-dong;HAN Ming-xiang;CHEN Wei;DONG Mei;LIU Ling;HOU Hao-bin;DING Zhen;LIU Xin-kuang;YAO Li(Graduate School,Anhui University of Chinese Medicine,Hefei 230038,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,China;Lu'an People's Hospital,Lu'an 237005,China;Hefei Binhu Hospital,Hefei 230601,China;Huai nan Hospital of Infectious Diseases,Huainan 232000,China;Hefei Second People's Hospital,Hefei 230011,China)

机构地区：[1]安徽中医药大学研究生院,合肥230038 [2]安徽中医药大学第一附属医院,合肥230031 [3]六安市人民医院,安徽六安237005 [4]合肥市滨湖医院,合肥230601 [5]淮南市传染病医院,安徽淮南232000 [6]合肥市第二人民医院,合肥230011

出　　处：《中国实验方剂学杂志》2020年第12期28-34,共7页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：安徽省新型冠状病毒感染的肺炎疫情应急科研攻关项目(202004a07020005)。

摘　　要：目的:分析安徽省新型冠状病毒感染的肺炎患者的一般情况及中医证候学特征,为临床诊治提供依据。方法:利用多中心横断面流行病学调查方法收集安徽省各定点医院144例新型冠状病毒肺炎患者。创建新型冠状病毒肺炎患者中医证候信息采集表,对患者的一般资料、病因病机、脉证资料、证型进行收集及频数统计,总结分析新型冠状病毒肺炎患者主要症状及证候分布特点。结果:144例新型冠状病毒感染的肺炎患者平均年龄(43.54±15.91)岁,男性多于女性(男女比9/7),患者年龄分布与性别差异有统计学意义(P<0.05),36.11%(52/144)的患者有武汉/湖北旅游/居史,63.89%(92/144)的患者有确诊患者密切接触史。临床主要以发热、咳嗽、泄泻、乏力、纳差等为主要证候表现。舌质以淡红舌和红舌为主;舌苔以腻苔为主;脉象以滑脉、数脉、濡脉为主。辨证分型以普通型为主(76.38%,110/144),其中多表现为湿阻肺脾证(56.25%,81/144)。普通型两组证型患者男女构成比与年龄分布差异无统计学意义。结论:安徽省新冠肺炎患者发病与肺脾关系密切,疫毒之邪夹湿是本病的主要病理因素,符合中医湿疫的表现,可兼见"热、毒、瘀"等特点。Objective:To analyze the general situation and traditional Chinese medicine(TCM) syndrome characteristics in patients with coronavirus disease-2019(COVID-19)in Anhui province,and to provide a basis for clinical diagnosis and treatment.Method:The 144 cases of COVID-19 patients in Anhui province were collected from designated hospitals by means of multi-center cross-sectional epidemiological survey.The TCM syndrome information collection table of patients with novel coronavirus pneumonia was created to collect the general data,etiology and pathogenesis,pulse and signs,syndrome type and frequency statistics of the patients,and then summarize and analyze the main symptoms and syndrome distribution characteristics of patients with novel coronavirus pneumonia.Result:The mean age of 144 patients with COVID-19 infection was(43.54±15.91)years old,and the number of males was larger than the number of females(9/7).The age distribution and gender difference of the patients were statistically significant(P<0.05).36.11%(52/144)of the patients had a history of travel/residence in Wuhan/Hubei province,and 63.89%(92/144)of the patients had a history of close contact with the confirmed patients.The main clinical manifestations included fever,cough,diarrhea,fatigue and poor tolerance.Light red tongue and red tongue were dominant in tongue quality,with mainly greasy coating,slippery pulse,rapid pulse and soft pulse were the main types of pulse.The main types of syndrome differentiation were the common type(76.38%,110/144),most of which were demonstrated as dampness obstructing the lung and spleen(56.25%,81/144).There was no significant difference in gender composition and age distribution between two groups.Conclusion:The pathogenesis of COVID-19 patients in Anhui province is closely related to the lung and spleen,and the dampness caused by pathogen of the epidemic virus is the main pathological factor of disease,which is in line with characteristics of dampness epidemic in TCM,also can see concurrently"heat,poison,stasis"for a cha

关 键 词：新型冠状病毒肺炎 中医证候 湿阻肺脾 湿热蕴肺 

分 类 号：R22[医药卫生—中医基础理论] R242[医药卫生—中医学]