胸部肿瘤患者辐射性肺炎的发生和预测因素  

Occurrence and perdictive factors of radiation pneumonitis in patients with thoracic tumor

作　　者：符伶俐 李萍 张芮 韩江龙 付振明 Fu Lingli;Li Ping;Zhang Rui;Han Jianglong;Fu Zhenming(Cancer Center,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院肿瘤中心,430060

出　　处：《国际肿瘤学杂志》2020年第2期107-111,共5页Journal of International Oncology

基　　金：国家自然科学基金(81472971、81773555)。

摘　　要：辐射性肺炎是胸部肿瘤放疗过程中的常见并发症,由此造成的呼吸衰竭是最严重的不良反应。辐射性肺炎的发生及其严重程度取决于多种因素,包括患者年龄、体力状况评分、吸烟状况、肺部基础情况、肿瘤大小、肿瘤位置、放化疗相关因素、炎症指标、单核苷酸多态性等。还有研究者将单光子发射计算机断层成像术、PET-CT等影像学检查应用于辐射性肺炎的预测,而其实用性仍有待加强。目前仍需进一步研究,找出预测辐射性肺炎发生的金标准。Radiation pneumonitis is a common complication in the radiotherapy for thoracic malignant tumors.And the resulting respiratory failure is one of the most serious side effects.The occurrence and severity of radiation pneumonitis depend on many factors such as age,performance status scores,smoking status,lung condition,tumor sizes,tumor location,chemoradiotherapy related factors,inflammatory factors and single-nucleotide polymorphism,et al.Some imaging examinations,for example single-photon emission computed tomography and PET-CT,have been used to predict radiation pneumonitis,while its usefulness remains to be strengthened.Further researches are still needed to find the gold standard in the prediction of radiation pneumonitis.

关 键 词：胸部肿瘤 放射疗法 辐射性肺炎 

分 类 号：R730[医药卫生—肿瘤]