西藏地区发作性疾病的分类及癫痫发作的相关研究  

A study on the classification of paroxysmal diseases and epilepsy seizures in Tibet

作　　者：何世华 卓玛[2] 赵玉华 严静[1,2] HE Shihua;ZHUO Ma;ZHAO Yuhua;YAN Jing(Department of Medicine,Tibet University,Lhasa 850000,China;Department of Neurology,the People's Hospital of Tibet Autonomous Region(TAR),Lhasa 850000,China)

机构地区：[1]西藏大学医学院,拉萨850000 [2]西藏自治区人民医院神经内科,拉萨850000

出　　处：《癫痫杂志》2020年第3期210-214,共5页Journal of Epilepsy

摘　　要：目的分析西藏地区人群常见发作性疾病的类型及特征,以助于提高发病类型的诊断,分析西藏地区人群癫痫发作的相关因素。方法回顾性分析2013年6月—2018年12月于西藏自治区人民医院神经内科住院治疗的510例发作性疾病并进行视频脑电图监测的患者临床资料。结果在510例发作性疾病患者中,发作性疾病类型共计35种,主要类型为:癫痫335例(65.69%)、心因性非痫性发作(Psychogenic nonepileptic seizures,PNES)86例(16.86%)。癫痫在男女性别中发病率有统计学差异(P<0.05);癫痫发病率在不同海拔高度、不同血红蛋白浓度中有统计学差异(P<0.05);大部分患者的发作病程超过2年(P<0.05);癫痫在发作频率及发作年龄中无差异性,但该地区癫痫患者以青年为主(34.51%)。结论在西藏地区人群中发作性疾病种类多样,癫痫性发作是其主要类型。癫痫患者发病和海拔高度存在一定性关系,癫痫发病率不会因血红蛋白升高而增加,发作病程多超过2年。Objective To analyze the types and characteristics of common paroxysmal diseases in order to improve the diagnosis of onset types and to analyze the related factors of epileptic seizures in Tibetan population.Methods 510 patients with paroxysmal diseases were enrolled in the Department of Neurology,People's Hospital of Tibet Autonomous Region from June 2013 to December 2018 and the video electroencephalogram(VEEG)data were analyzed.Results Among the 510 patients,there were 35 types of paroxysmal diseases,335 cases(65.69%)of seizures and 86 cases(16.86%)of psychogenic non-epileptic seizures(PNES).There were significant differences in the incidence of seizures between male and female patients(P<0.05),the incidence of seizures were different at different altitude and the concentration of hemoglobin(P<0.05),the course of seizures was always more than 2 years(P<0.05),and the frequency and age of seizures were higher,but there were no significant difference,and epileptic patients in Tibet were more likely to be young adults(34.51%).Conclusions There are many kinds of paroxysmal diseases in Tibetan population,and epileptic seizures are the main type.There was a qualitative relationship between the incidence of epilepsy and altitude.The incidence of epilepsy didn’t increase along with the increase of hemoglobin,and the course of seizures was mostly more than 2 years.

关 键 词：发作性疾病 癫痫 海拔 西藏地区 

分 类 号：R742.1[医药卫生—神经病学与精神病学]