Effects of crystal structure on the activity of MnO2 nanorods oxidase mimics  

作　　者：Yanxia Meng Kunfeng Zhao Zhaokun Zhang Peng Gao Jing Yuan Ting Cai Qin Tong Gang Huang Dannong He 

机构地区：[1]School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,516 Jungong Road,Shanghai,200093,China [2]School of Materials Science and Engineering,Shanghai Jiao Tong University,800 Dongchuan Road,Shanghai,200240,China [3]National Engineering Research Center for Nanotechnology,28 East Jiangchuan Road,Shanghai,200241,China [4]Shanghai University of Medicine and Health Sciences,279 Zhouzhu Road,Shanghai,201318,China [5]Ningbo Fundenergy Co.,Ltd.,699 Haicheng Road,Ningbo,315200,China

出　　处：《Nano Research》2020年第3期709-718,共10页纳米研究（英文版）

基　　金：This work was supported by the National Key R&D Program of China(No.2016YFA0202900);China Postdoctoral Science Foundation(No.2018M642021);the National Natural Science Foundation of China(No.21677095);Minhang District Science and Technology Project of Shanghai(No.2019MH-MS02).

摘　　要：The crystal structures would directly affect the physical and chemical properties of the surface of the material,and would thus influence the catalytic activity of the material.α-MnO2,β-MnO2 andγ-MnO2 nanorods with the same morphology yet different crystal structures were prepared and tested as oxidase mimics using 3,3’,5,5’-tetramethylbenzidine(TMB)as the substrate.β-MnO2 that exhibited the highest activity had a catalytic constant of 83.75μmol·m^−2·s^−1,2.7 and 19.0 times of those ofα-MnO2 andγ-MnO2(30.91 and 4.41μmol·m^−2·s^−1),respectively.The characterization results showed that there were more surface hydroxyls as well as more Mn4+on the surface of theβ-MnO2 nanorods.The surface hydroxyls were conducive to the oxidation reaction,while Mn4+was conducive to the regeneration of surface hydroxyls.The synergistic effect of the two factors significantly improved the activity ofβ-MnO2 oxidase mimic.Usingβ-MnO2,aβ-MnO2-TMB-GSH system was established to detect the content of glutathione(GSH)rapidly and sensitively by colorimetry.This method had a wide detection range(0.11-45μM)and a low detection limit(0.1μM),and had been successfully applied to GSH quantification in human serum samples.

关 键 词：crystal phase structure MNO2 oxidase mimics surface hydroxyls 3 3’ 5 5’-tetramethylbenzidine(TMB) GLUTATHIONE 

分 类 号：O64[理学—物理化学]