3D-Slicer软件在难治性癫痫外科手术计划可视化中的运用  

Application of 3D-Slicer software in visualization of surgical planning for intractable epilepsy

作　　者：李佳[1] 林久銮[1] 周文静[1] 宋宪成[1] 王海祥[1] 丰倩[1] 阮静[1] 王思瑜 LI Jia;LIN Jiu-luan;ZHOU Wen-jing(Department of Epilepsy Center, Yuquan Hospital Tsinghua University, Beijing 100040, China)

机构地区：[1]清华大学玉泉医院癫痫中心,北京100040

出　　处：《临床神经外科杂志》2020年第3期306-310,共5页Journal of Clinical Neurosurgery

摘　　要：目的探讨3D-Slicer软件在难治性癫痫外科手术计划中辅助应用价值。方法对清华大学玉泉医院癫痫中心2018年1月—2018年6月行病灶切除术的17例患者(男11例,女6例),运用3D-Slicer软件以DICOM格式导入患者的影像资料,进行影像重建,获得3D可视化图像,充分展示脑沟回及血管的三维位置关系,规划手术方案,并行术前模拟手术操作。结果本组患者均按最佳的模拟手术方案进行手术,均顺利完成显微镜下切除发作起源区。患者术后均未出现严重并发症。术后2周和6个月复查MRI,显示病灶切除部位和范围达到预期效果。结论运用3D-Slicer软件进行术前三维重建并辅助制定手术计划,获得可视化的解剖信息,以此指导术者设计手术切口、选择手术入路保护功能区,可提高手术成功率;并在脑功能保护、减少术后并发症方面发挥作用。Objective To explore the application value of 3D-Slicer software in surgical planning of intractable epilepsy.Methods 17 patients(11 males and 6 females)who underwent focal resection in Yuquan Hospital of Tsinghua University from January 2018 to June 2018 were selected.The image data of 17 patients with intractable epilepsy were imported by using 3D-Slicer software in DICOM format and the images were reconstructed.The 3D visualization images were obtained,which fully displayed the three-dimensional position relationship between the sulcus gyrus and the blood vessels.The operation was planned and simulated according to the 3D visualization images.Results All cases were operated according to the best simulated operation plan,and finally the epileptogenic focus was removed under the microscope.There were no serious complications after the operation.The resection site achieved the desired effect by re-examining the MRI 2 weeks and 6 months after the operation.Conclusions Using 3D-Slicer software to reconstruct three-dimensional images before operation and to assist in making surgical plans.Visual anatomical information can be obtained,which can guide the operator to design surgical incision and select surgical approach to protect functional areas.It can improve the success rate of surgery,and play a role in brain function protection and reduce postoperative complications.

关 键 词：难治性癫痫 3D-Slicer软件 手术计划 

分 类 号：R742.1[医药卫生—神经病学与精神病学]