抗阻训练改善中老年男性原发性高血压患者功能性抗交感的疗效观察  

Resistance training improves functional sympatholysis in persons with primary hypertension

作　　者：贾钧[1] 王晨宇[1] Jia Jun;Wang Chenyu(Research Center of Physical Health and Culture,Zhengzhou University of Aeronautics,Zhengzhou 450046,China)

机构地区：[1]郑州航空工业管理学院,体育健康与文化研究中心,郑州450046

出　　处：《中华物理医学与康复杂志》2020年第4期348-353,共6页Chinese Journal of Physical Medicine and Rehabilitation

基　　金：河南省重点科技攻关项目(152102310117)。

摘　　要：目的探讨12周抗阻训练对原发性高血压患者骨骼肌功能性抗交感的影响。方法将30例未经治疗的中老年男性1级原发性高血压患者纳入高血压组,同时选取30例血压正常的健康受试者纳入对照组,2组受试者均进行12周(3次/周)渐进性抗阻训练。于干预前、后分别利用冷加压实验(CPT)激活受试者交感神经系统,测定其安静及握力运动时前臂血液动力学变化。交感缩血管反应参数用CPT诱导肱动脉电导(FVC)的变化率(%FVC)表示,功能性抗交感参数(即肌肉收缩抑制交感缩血管反应的能力)用握力运动时与安静时交感缩血管反应的差值(△%FVC)表示。结果干预前2组受试者△%FVC组间差异无统计学意义[高血压组为(7.4±8.6)%,对照组为(7.9±11.3)%,P=0.883]。干预后与组内干预前比较,发现2组受试者△%FVC[高血压组为(17.1±5.8)%,对照组为(16.9±9.7)%]均明显升高(P<0.05),此时组间差异仍无统计学意义(P>0.05)。结论12周抗阻训练能明显改善中老年男性原发性高血压患者功能性抗交感,同时发现血压升高本身并不能破坏机体功能性抗交感。Objective To explore the effect of twelve weeks of resistance training on the functional sympatholysis of the skeletal muscles in persons with primary hypertension.Methods Thirty untreated adult men with stage 1 essential hypertension(SBP/DBP:140-159/90-99mmHg)formed a hypertension group,while thirty healthy counterparts(SBP/DBP:90-120/60-80mmHg)served as a control group.Both groups underwent 12 weeks of progressive resistance training,3 times a week.Before and after the intervention,any changes in forearm haemodynamics at rest were measured,along with handgrip after activation of the sympathetic nerve using a cold pressor test(CPT).The sympathetic vasoconstriction response was represented by the rate of change in brachial vascular conductance(%FVC)induced by the CPT,and the ability to suppress sympathetic vasoconstrictor responses using muscle contractions(functional sympatholysis)was quantified as the difference in sympathetic vasoconstrictor response between the handgrip test and at rest(△%FVC).Results There were no significant differences between the two groups in their average△%FVCs before the intervention.After the intervention,significant increases were observed in both groups,but there was still no significant difference between the two groups′average△%FVCs.Conclusion Twelve weeks of resistance training can improve the functional sympatholysis of adult men with essential hypertension.Their elevated blood pressure does not impair functional sympatholysis.

关 键 词：高血压 抗阻训练 血液动力学 交感缩血管反应 功能性抗交感 

分 类 号：R544[医药卫生—心血管疾病]