轻度认知障碍危险因素研究进展  

RESEARCH ADVANCES IN RISK FACTORS FOR MILD COGNITIVE IMPAIRMENT

作　　者：张丽娜[1] 张俊青 侯继文 郭宗君[1] ZHANG Lina;ZHANG Junqing;HOU Jiwen;GUO Zongjun(Department of Geriatrics, The Affiliated Hospital of Qingdao University, Qingdao 266100, China)

机构地区：[1]青岛大学附属医院老年医学科,山东青岛266100

出　　处：《青岛大学学报（医学版）》2020年第3期331-336,共6页Journal of Qingdao University(Medical Sciences)

基　　金：山东省自然科学基金面上项目(ZR2012HM049)。

摘　　要：轻度认知障碍(MCI)是痴呆的早期阶段,指记忆力或其他认知功能进行性减退,但不影响日常生活能力,且未达到痴呆的诊断标准。近年来,越来越多的研究表明,MCI与诸多因素相关,如生活方式、系统性疾病、慢性炎症、肠道微生态及遗传因素等。本文对国内外相关研究进展进行综述,旨在识别有罹患认知障碍风险者,以实施早期干预和治疗。Mild cognitive impairment(MCI)is an early stage of dementia and refers to the progressive deterioration of memory or other cognitive functions which does not affect the activities of daily living and does not meet the diagnostic criteria for dementia.In recent years,more and more studies have shown that MCI is associated with many factors,such as lifestyle,systemic diseases,chronic inflammation,intestinal microecology,and genetic factors.This article reviews the relevant research advances,aiming to identify the people at a risk of cognitive impairment and implement early intervention and treatment.

关 键 词：认知功能障碍 危险因素 综述 

分 类 号：R741[医药卫生—神经病学与精神病学] R181.13[医药卫生—临床医学]