复发性鼻咽癌的治疗现状  

Treatment of Recurrent Nasopharyngeal Carcinoma

作　　者：刘欣雨 刘鸣[1] LIU Xinyu;LIU Ming(Department of Otorhinolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第二医院耳鼻咽喉头颈外科,哈尔滨150001

出　　处：《医学综述》2020年第12期2360-2365,共6页Medical Recapitulate

摘　　要：鼻咽癌是耳鼻咽喉科常见的恶性肿瘤之一,发病存在明显的地域性差异,我国以南部沿海地区高发,多以放疗联合顺铂化疗作为首选治疗方案,治疗后复发率较高。不同类型的鼻咽癌复发患者可以选择不同的治疗方案,其中以全身治疗、多方案联合化疗为优;再放疗和外科手术是局部复发性鼻咽癌患者的最常用治疗方式;其他治疗方式,如免疫治疗、靶向治疗、重离子再照射治疗等新型治疗方式尚处于试验阶段,疗效仍需临床验证。Nasopharyngeal carcinoma(NPC)is one of the common malignant tumors in otorhinolaryngology.There are obvious regional differences in the incidence of nasopharyngeal carcinoma that in the southern coastal areas of China the incidence is high.Radiotherapy combined with cisplatin chemotherapy is the preferred treatment,and the recurrence rate is high after treatment.Different types of recurrent nasopharyngeal carcinoma patients can choose different treatment schemes,among which systemic therapy and multi-scheme combined chemotherapy are the best;re-radiation therapy and surgery are the most common treatment methods for local recurrent nasopharyngeal carcinoma patients;other treatment methods,such as immunotherapy,targeted therapy and heavy ion re-irradiation are still in the experimental stage,still needing clinical validation for the curative effect.

关 键 词：鼻咽癌 化疗 靶向治疗 再放疗 免疫疗法 

分 类 号：R739.6[医药卫生—肿瘤]