原发性玻璃体视网膜淋巴瘤的诊断进展  

Recent progress in the diagnosis of primary vitreoretinal lymphoma

作　　者：刘师学 常青 Liu Shixue;Chang Qing(Department of Ophthalmology,Shanghai Eye&ENT Hospital of Fudan University,Shanghai 200031,China)

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海200031

出　　处：《中华眼底病杂志》2020年第6期474-478,共5页Chinese Journal of Ocular Fundus Diseases

摘　　要：原发玻璃体视网膜淋巴瘤(PVRL)是罕见的高度恶性非霍奇金淋巴瘤,因临床表现特异性不佳常被称为"伪装综合征"。对其早期、正确地诊断较为困难。PVRL在影像学上有特异性表现,但表现多样;病理细胞学诊断仍是PVRL诊断的金标准。其诊断需要结合临床表现、影像学特点、病理诊断和分子生物学诊断等综合分析判定。随着技术的进步,特别是对于细胞因子的检测、基因表达的研究,PVRL的分子生物学诊断成为研究热点和重要的辅助诊断手段。Primary vitreoretinal lymphoma(PVRL)is a rare and aggressive high-grade non-Hodgkin lymphoma.PVRL always with non-specific symptoms and has therefore been called as masquerade syndrome.Thus,the early and correct diagnosis of PVRL is a difficulty.For PVRL,the imaging findings can be specific but variety,histological diagnosis is still the gold standard.Its diagnosis needs to be combined with clinical manifestations,imaging features,pathological diagnosis and molecular biology.With the advancement of technology,especially in the field of the cytokines detection and the gene expression profiling research,molecular biology diagnosis of PVRL is becoming a research hotspot and an important auxiliary diagnostic method.

关 键 词：眼肿瘤/诊断 淋巴瘤 大B细胞 弥漫性 综述 

分 类 号：R739.7[医药卫生—肿瘤]