血管减压术治疗原发性三叉神经痛的疗效及对患者焦虑抑郁的影响  

Efficacy of microvascular decompression in treatment of primary trigeminal neuralgia and its effects on the patients′anxiety and depression

作　　者：郭贤放 廖声潮[1] 莫凯[1] 邝泓[1] GUO Xian-fang;LIAO Sheng-chao;MO Kai(Department of Neurosurgery, the Second Affiliated Hospital of Guangxi Medical University, Nanning 530007, China)

机构地区：[1]广西医科大学第二附属医院神经外科,南宁530007

出　　处：《中国临床新医学》2020年第6期584-586,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西卫健委科研课题(编号:Z2016283)。

摘　　要：目的观察微血管减压术(MVD)治疗原发性三叉神经痛的临床疗效,以及治疗前后患者焦虑、抑郁变化情况。方法选择2014-09~2018-12在该院神经外科接受MVD治疗的原发性三叉神经痛患者80例。应用Zung抑郁自评量表(SDS)及Zung焦虑自评量表(SAS)对患者治疗前及治疗后第3个月抑郁、焦虑情况进行评分和比较。分析MVD对原发性三叉神经痛的临床疗效。结果经过MVD治疗,80例患者中治愈63例,显效13例,有效2例,无效2例,无复发病例。80例患者中,治疗前有抑郁者24例(30.00%),焦虑者20例(25.00%);治疗后,有抑郁者8例(10.00%),焦虑者5例(6.25%),治疗前后比较差异均有统计学意义(P<0.05)。与治疗前比较,治疗后SAS、SDS评分均显著降低(P<0.05)。结论MVD治疗原发性三叉神经痛临床效果良好,患者的焦虑、抑郁症状得到显著改善。Objective To observe the clinical effects of microvascular decompression(MVD)on primary trigeminal neuralgia and the changes of anxiety and depression in the primary trigeminal neuralgia patients before and after treatment.Methods Eighty patients with primary trigeminal neuralgia who underwent MVD in the Department of Neurosurgery,the Second Affiliated Hospital of Guangxi Medical University from September 2014 to December 2018 were selected.Zung Self-rating Depression Scale(SDS)and Zung Self-rating Anxiety Scale(SAS)were used to score and compare the depression and anxiety of the patients before and 3 months after treatment.The clinical effect of MVD on primary trigeminal neuralgia was analyzed.Results Of the 80 cases,63 cases were cured,13 cases markedly effective,2 cases effective,2 cases ineffective,and no recurrence was found after MVD treatment.Before treatment,of the 80 cases,24 cases were depressed(30.00%)and 20 cases were anxious(25.00%);after treatment,8 cases were depressed(10.00%)and 5 cases were anxious(6.25%),and the differences were statistically significant(P<0.05).Compared with those before treatment,SAS and SDS scores were significantly reduced after treatment(P<0.05).Conclusion MVD is effective in treatment of primary trigeminal neuralgia,and the patients′anxiety and depression symptoms are significantly improved.

关 键 词：原发性三叉神经痛 焦虑 抑郁 微血管减压术 

分 类 号：R741.05[医药卫生—神经病学与精神病学]