腹腔镜前列腺癌根治术治疗早期局限性前列腺癌的效果  

Effect of laparoscopic radical prostatectomy for early localized prostate cancer

作　　者：庞程[1] 谢兴年[1] 杨志坚[1] 欧光鑫[1] 刘肇华[1] 陈敏坚[1] PANG Cheng;XIE Xing-nian;YANG Zhi-jian(The First People’s Hospital of Zhaoqing,Zhaoqing 526060,China)

机构地区：[1]肇庆市第一人民医院,526060

出　　处：《中国现代药物应用》2020年第12期1-3,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析早期局限性前列腺癌以腹腔镜前列腺癌根治术治疗的临床效果。方法50例早期局限性前列腺癌患者,采用随机数字表法分为对照组和观察组,每组25例。对照组患者行传统开腹经耻骨后前列腺癌根治术治疗,观察组患者行腹腔镜前列腺癌根治术治疗。比较两组患者手术情况、并发症发生情况、尿流动力学指标。结果观察组患者手术时间、胃肠功能恢复时间、引流管拔除时间以及住院时间均短于对照组,术中出血量少于对照组,差异具有统计学意义(P<0.05)。观察组患者并发症发生率8.00%低于对照组的32.00%,差异具有统计学意义(P<0.05)。治疗后,观察组患者残余尿量(PVR)、充盈期膀胱顺应性(BC)、最大尿流率(Qmax)、最大尿流率时逼尿肌压力(Pdet at Qmax)分别为(87.4±9.5)ml、(15.3±1.7)ml/cm H2O(1 cm H2O=0.098 kPa)、(6.5±0.3)ml/s、(93.8±8.7)cm H2O,均优于对照组的(157.5±11.9)ml、(17.8±1.6)ml/cm H2O、(3.7±0.2)ml/s、(73.4±7.6)cm H2O,差异具有统计学意义(P<0.05)。结论早期局限性前列腺癌患者采用腹腔镜前列腺癌根治术治疗的效果突出,手术时间、胃肠功能恢复、引流管拔除以及住院时间较短,术中出血量和术后并发症较少,尿流动力学改善,值得临床推广应用。Objective To analyze the clinical effect of laparoscopic radical prostatectomy for early localized prostate cancer.Methods A total of 50 patients with early localized prostate cancer were divided into control group and observation group by random numerical table,with 25 cases in each group.The patients in the control group were treated with traditional open radical prostatectomy and the patients in the observation group were treated with laparoscopic radical prostatectomy.The surgical situation,occurrence of complications and urodynamic indexes were compared between the two groups.Results The surgical time,recovery time of gastrointestinal function,removal time of drainage tube and hospitalization time of the observation group were shorter than those of the control group,and amount of intraoperative hemorrhage was less than that of the control group.The difference was statistically significant(P<0.05).The incidence of complications 8.00%of the observation group was lower than that of the control group 32.00%,and the difference was statistically significant(P<0.05).After treatment,the post-void residual(PVR),bladder compliance(BC),maximum urinary flow rate(Qmax)and pressure of detrusor at Qmax(Pdet at Qmax)of the observation group were(87.4±9.5)ml,(15.3±1.7)ml/cm H2O(1 cm H2O=0.098 kPa),(6.5±0.3)ml/s and(93.8±8.7)ml respectively,which were all better than those of the control group(157.5±11.9)ml,(17.8±1.6)ml/cm H2O,(3.7±0.2)ml/s and(73.4±7.6)cm H2O in the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic radical prostatectomy for early localized prostate cancer is effective in the treatment of patients with early localized prostate cancer,with shorter surgical time,recovery time of gastrointestinal function,removal time of drainage tube,hospitalization time,and less intraoperative hemorrahge and postoperative complications,as well as improved urodynamics.It is worthy of clinical promotion and application.

关 键 词：腹腔镜前列腺癌根治术 早期局限性 前列腺癌 手术情况 

分 类 号：R73[医药卫生—肿瘤]