抗NMDA受体脑炎的临床特点和脑电图表现  

Clinical Characteristics and Electroencephalogram of Anti-NMDA Receptor Encephalitis

作　　者：马美刚[1] 吴原[1] MA Mei-gang;WU Yuan(Department of Neurology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China)

机构地区：[1]广西医科大学第一附属医院神经内科,广西南宁530021

出　　处：《医学信息》2020年第12期20-23,共4页Journal of Medical Information

基　　金：国家自然科学基金(编号:81760242);广西医药卫生自筹经费计划课题(编号:Z20180956)。

摘　　要：抗N-甲基-D-天冬氨酸(NMDA)受体脑炎是自身免疫性脑炎的一种,其临床表现复杂多样,主要为精神行为异常、癫痫发作、肌张力障碍和意识障碍等,易被误诊为精神分裂症和病毒性脑炎。脑电图是评估脑功能的良好指标,抗NMDA受体脑炎的脑电图表现具有一定的特异性,因此了解抗NMDA受体脑炎脑电图的特点对于疾病诊断及评估预后具有重要意义。本文就抗NMDA受体脑炎的临床表现及脑电图特点进行综述,以期为抗NMDA受体脑炎的脑电图诊断提供参考。Anti-NMDA receptor encephalitis is a type of autoimmune encephalitis.Its clinical manifestations are complex and diverse,mainly for mental behavior abnormalities,seizures,dystonia and consciousness disorders,etc,which are easily misdiagnosed as schizophrenia and virus encephalitis.EEG is a good indicator for evaluating brain function.The EEG performance of anti-NMDA receptor encephalitis has certain specificity,so understanding the characteristics of anti-NMDA receptor encephalitis EEG is of great significance for disease diagnosis and prognosis evaluation.This article reviews the clinical manifestations and EEG characteristics of anti-NMDA receptor encephalitis in order to provide a reference for the diagnosis of anti-NMDA receptor encephalitis.

关 键 词：抗NMDA受体 脑炎 脑电图 

分 类 号：R741.044[医药卫生—神经病学与精神病学]