颌骨囊性病变囊内压对开窗术后不同时间段体积缩小速度的影响  

Effect of intracapsular pressure on the speed of shrinkage in different time periods after decompression

作　　者：熊贤斌 吴元元 郑旸[1] 丁旭[1] 武和明[1] 吴煜农[1] 宋晓萌[1] XIONG Xianbin;WU Yuanyuan;ZHENG Yang;DING Xu;WU Heming;WU Yunong;SONG Xiaomeng(Jiangsu Key Laboratory of Oral Diseases,Department of Oral and Maxillofacial Surgery,Affiliated Hospital of Stomatology,Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学口腔疾病研究江苏省重点实验室,南京医科大学附属口腔医院口腔颌面外科,江苏南京210029

出　　处：《口腔医学》2020年第5期411-415,431,共6页Stomatology

基　　金：国家自然科学基金(81772887);江苏省医学创新团队资助项目(CXTD2017036);江苏省高校优势学科建设工程(2018-87)。

摘　　要：目的探讨颌骨囊性病变开窗减压后不同时间段体积缩小速度与囊内压之间的关系。方法纳入南京医科大学附属口腔医院2018年4月到2019年10月影像学及病理学诊断为颌骨囊性病变且采用开窗减压术进行治疗的25例患者。术前使用压力传感器测量出囊内压力,使用Mimics 17.0软件分别在术前及术后3、6、12个月测量囊腔体积,计算囊性病变不同时间段的体积缩小速度(speed of shrinkage,SS,SS0-3:术后前3个月体积缩小速度;SS3-6:术后3到6月体积缩小速度;SS6-12:术后6~12个月体积缩小速度)。统计学方法采用方差分析及相关性检验,当P<0.05时差异有统计学意义。结果SS0-3,SS3-6,SS6-12两两对比差异具有统计学意义。SS0-3与囊内压力成负相关(r=-0.5295,n=25,P<0.01),与年龄成负相关(r=-0.5866,n=25,P<0.01)。囊内压与术前囊腔的体积成负相关(r=-0.4487,n=25,P<0.05)。SS0-3与成人术前囊腔体积成正相关(r=0.4546,n=20,P<0.05)。结论颌骨囊性病变开窗减压术后不同时间段体积缩小速度与囊内压力密切相关。Objective To investigate the relationship between the speed of shrinkage(SS) and the intracapsular pressure during indicated time after decompression. Methods Twenty-five patients who were diagnosed with cystic lesions of jaw bone by both imaging and pathological examination from April 2018 to October 2019 in the Affiliated Stomatological Hospital, Nanjing Medical University were enrolled in this study. Pressure sensors were utilized to measure the intracapsular pressure before operation. The volume of the cyst lesions was determined using Mimics17.0 software before operation and 3, 6, 12 months after the surgery. Then the speed of shrinkage was calculated at different time periods(SS0-3: the rate of volume reduction in the first 3 months after surgery, SS3-6: the rate of volume reduction during 3 to 6 months after surgery, SS6-12: the rate of volume reduction during 6 to 12 months after surgery). The Student’s ANOVA and linear correction analysis were utilized to evaluate the statistical significance of the results and P<0.05 was considered significant. Results ANOVA statistical analysis showed that there were significant differences between SS0-3, SS3-6 and SS6-12. SS0-3 was negatively correlated with intracapsular pressure(r=-0.5295, n=25, P<0.01). SS0-3 was negatively correlated with age(r=-0.5866, n=25, P<0.01). The intracapsular pressure was negatively associated with preoperative volume(r=-0.4487,n=25,P<0.05). SS0-3 was positively correlated with the preoperative cystic volume of adults(r=0.4546, n=20,P<0.05). Conclusion The speed of shrinkage in different time periods after decompression is closely related to the intracapsular pressure of cystic lesions.

关 键 词：颌骨囊性病变 囊内压力 开窗减压术 体积缩小速度 

分 类 号：R782[医药卫生—口腔医学] R739.82[医药卫生—临床医学]