肌肉测量与PG-SGA评估在胃癌患者营养评估中的相关性研究  

Skeletal muscle measurement and PG-SGA in nutritional assessment of patients with gastric cancer

作　　者：彭海艳 戴静[1] 王文博[1] 彭晋[1] 夏泠 李怡 谢丛华[1] 许红霞 石汉平 周福祥[1] Peng Haiyan;Dai Jing;Wang Wenbo;Peng Jin;Xia Ling;Li Yi;Xie Conghua;Xu Hongxia;Shi Hanping;Zhou Fuxiang(Department of Radiation and Medical Oncology,Zhongnan Hospital,Wuhan University/Key Laboratory of Tumor Biology Behavior of Hubei Province/Clinical Cancer Study Center of Hubei Province,Wuhan 430071,Hubei,China;Department of Hematology and Oncology,Shenzhen University General Hospital,Shenzhen 518000,Guangdong,China;Department of Clinical Nutrition,Third Affiliated Hospital of Third Military Medical University,Chongqing 400042,China;Department of Gastrointestinal Surgery,Beijing Shijitan Hospital,Capital Medical University/the Ninth Clinical Medical College of Peking University,Beijing 100038,China)

机构地区：[1]武汉大学中南医院放化疗科/湖北省肿瘤生物学行为重点实验室/湖北省肿瘤医学临床研究中心,武汉430071 [2]深圳大学总医院血液肿瘤科,深圳518000 [3]陆军军医大学第三附属医院临床营养科,重庆400042 [4]首都医科大学附属北京世纪坛医院/北京大学第九临床医学院胃肠外科,北京100038

出　　处：《肿瘤代谢与营养电子杂志》2020年第2期188-192,共5页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：国家重点研发计划项目(2017YFC1309200)。

摘　　要：目的探讨骨骼肌指数(SMI)及骨骼肌密度(SMD)与患者主观整体评估(PG-SGA)在胃癌患者营养评估中的相关性。方法在全国肿瘤患者营养调查平台纳入2017年1月至2019年11月武汉大学中南医院的118例胃癌患者作为主要研究对象,收集其基本信息和营养评分,通过我院影像科影像归档和通信系统(PACS)纳入符合要求的第三腰椎层面的影像学图像,计算SMI及SMD的数值;最后运用Pearson相关分析法分析SMI、SMD与PG-SGA评分的相关性。结果118例胃癌患者SMI均值为(34.34±8.01)cm ^2/m ^2,95%CI=32.78~35.84,SMD均值为(42.44±7.34)HU,95%CI=41.06~43.97,男性均高于女性(P<0.05);PG-SGA评分范围在1~20分之间,均值为(6.73±4.30)分,95%CI=5.91~7.56;SMI与PG-SGA评分具有显著负相关性(相关系数r=-0.608,P<0.001),但SMD与PG-SGA评分无明显相关性(r=-0.045,P=0.651)。结论在胃癌中,SMI与PG-SGA这两种评估方式对患者营养状况的评定具有一致性。Objective To investigate the correlation between skeletal muscle index(SMI),skeletal muscle density(SMD)and PG-SGA scores in nutrition assessment among gastric cancer patients.Methods A total of 118gastric cancer patients from Zhongnan Hospital of Wuhan University from January 2017 to November 2019 were screened and included from National Cancer Patient Nutrition Survey Platform.The nutrition scores and other basic information were collected,and then we passed through the PACS system in the imaging department of our hospital to find the images in the 3rd lumbar spine plane that we needed.After finished calculating the SMI and SMD,Pearson correlation analysis was used to analyze the correlation between the PG-SGA score and SMI,SMD.Results Among these 118 patients with gastric cancer,the mean level of SMI was about(34.34±8.01)cm^ 2/m^ 2,95%confidence interval(95%CI)was from 32.78 to 35.84,and the average of SMD was(42.44±7.34)HU,95%CI was from 41.06 to 43.97.Men were both higher than women in the two characteristics(P<0.05).PG-SGA scores ranged from 1 to 20,with an average of(6.73±4.30),and 95%CI was from 5.91 to 7.56.There was a significant correlation between SMI and PG-SGA scores(r=-0.608,P<0.01),but there was no significant correlation between SMD and PG-SGA scores(r=-0.045,P=0.651).Conclusion In gastric cancer,the SMI and PG-SGA are consistent in assessing the nutritional status of patients.

关 键 词：骨骼肌指数 骨骼肌密度 胃癌患者 营养评估 

分 类 号：R735.2[医药卫生—肿瘤] R459.3[医药卫生—临床医学]