湛江地区甲状腺癌发生与ABO血型分布的相关性  

Correlation between the incidence of thyroid cancer and the distribution of ABO blood types in Zhanjiang

作　　者：覃文懿 陈明 官成浓 徐祖敏 李建文 陈小东 张智 陈祝萍 孙丽 QIN Wen-yi;CHEN Ming;GUAN Cheng-nong;XU Zu-min;LI Jian-wen;CHEN Xiao-dongl;ZHANG Zhi;CHEN Zhu-ping;SUN Li(Department of Vascular,Thyroid and Breast Surgery,the Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,China;The Central Blood Station of Zhanjiang,Zhanjiang 524002,China;Guangdong Medical University,Dongguan 52380&China)

机构地区：[1]广东医科大学附属医院血管甲状腺乳腺外科,广东湛江524001 [2]广东省湛江市中心血站,广东湛江524002 [3]广东医科大学,广东东莞523808

出　　处：《广东医科大学学报》2020年第3期304-306,共3页Journal of Guangdong Medical University

摘　　要：目的 探讨广东湛江地区甲状腺癌与ABO血型的相关性.方法 回顾性分析2013年1月至2018年12月在广东医科大学附属医院行手术治疗的甲状腺癌患者的ABO血型及手术病理资料,与湛江地区中心血站同期健康献血人群ABO血型分布进行比较,分析甲状腺癌与ABO血型之间的关系.结果 不同血型甲状腺癌患者的年龄、性别、病理分型比较,差异均无统计学意义(P>0.05);甲状腺癌患者ABO血型分布为AB>B>A>O,与对照组比较差异有统计学意义(P<0.01);非条件Logistic回归分析显示血型AB、B可增加甲状腺癌发病的危险(P<0.01或0.05);血型O可降低甲状腺癌发病的危险(P<0.01).结论 广东湛江地区甲状腺癌发病与ABO血型存在一定的关系,AB型血及B型血人群的甲状腺癌罹患率明显升高;O型血者为甲状腺癌的低风险人群.Objective To explore the correlation between thyroid cancer and blood type in Zhanjiang.Methods The ABO blood types and surgical and pathological data of patients with thyroid cancer who underwent surgical treatment in the Affiliated Hospital of Guangdong Medical University from January 2013 to December 2018 were retrospectively analyzed,and compared with the distribution of blood types of healthy blood donors in the central blood stations in Zhanjiang over the same period.The correlation between thyroid cancer and ABO blood types was analyzed.Results There were no significant differences in age,gender,or pathological type of thyroid cancer patients with different blood types(P>0.05).The blood type distribution of the thyroid cancer patients was AB>B>A>0,which showed a significant difference compared with that in the Control Group(P<0.01).The unconditional Logistic regression analysis revealed that the AB and B blood type could increase the risk of thyroid cancer(P<0.01 or 0.05)while the O blood type could reduce the risk of thyroid cancer(P<0.01).Conclusion There is certain correlation between the incidence of thyroid cancer and ABO blood types in Zhanjiang,Guangdong.The population with the AB and B blood types has a significantly increased incidence of thyroid cancer whereas the population with the O blood type is the population with a relatively low risk of thyroid cancer.

关 键 词：甲状腺癌 ABO血型 

分 类 号：R736.1[医药卫生—肿瘤]