3.0T MRI常规序列联合DTI及1H-MRS在颅内肿瘤中的诊断价值  

Diagnostic value of conventional 3.0T MRI with diffusion tensor imaging and 1H-magnetic resonance spectrum in intracranial tumors

作　　者：刘永辉[1] 黎海滨[1] 李素娟 陈锦灿[1] 邹光成[1] LIU Yong-hui;LI Hai-bin;LI Su-juan;CHEN Jin-can;ZOU Guang-cheng(Department of Radiology,Zhaoqing First People's Hospital,Zhaoqing 526000,China)

机构地区：[1]广东省肇庆市第一人民医院放射科,广东肇庆526000

出　　处：《广东医科大学学报》2020年第3期317-321,共5页Journal of Guangdong Medical University

摘　　要：目的 探讨3.0T MRI常规序列联合DTI及1H-MRS在颅内肿瘤中的诊断价值.方法 60例病理证实的颅内肿瘤患者接受MRI联合DTI及1H-MRS检查,分析DTI数据、代谢物水平改变与肿瘤病理分级的相关性.结果 不同病理类型颅内肿瘤的肿瘤实质区、瘤周水肿区FA、MD、RA、VR值均低于对侧正常脑组织(P<0.01或0.05),肿瘤实质区FA、RA值低于瘤周水肿区(P<0.05).脑白质纤维束示踪成像显示肿瘤周围受压或破坏.MRS显示不同肿瘤中Cho/Cr、NAA/Cr、Cho/NAA比值差异有统计学意义(P<0.01).结论 3.0T MRI常规序列联合DTI及1H-MRS有助于评价颅内肿瘤性质、病理分级、浸润程度.Objective To evaluate the diagnostic value of conventional 3.0 T MRI with diffusion tensor imaging(DTI) and ~1 H-magnetic resonance spectrum(MRS) in intracranial tumors. Methods Conventional MRI, DTI and ~1 H-MRS were performed in 60 cases of pathologically-confirmed intracranial tumors. The correlation between tumor pathologic grades and DTI data or metabolite levels was analyzed. Results The FA, MD, RA and VR in tumor parenchyma and peritumoral edema were lower than those in contralateral normal tissue(P<0.01 or 0.05), while FA and RA were lower in tumor parenchyma than in peritumoral edema(P<0.05). White matter tractography showed peritumoral compression or damage. MRS revealed that Cho/Cr, NAA/Cr and Cho/NAA ratios were significantly different in pathologic types of intracranial tumors(P<0.01). Conclusion Conventional 3.0 T MRI with DTI and ~1 H-MRS can be helpful to evaluate the characters, pathologic types and invasive degree in intracranial tumors.

关 键 词：颅内肿瘤 磁共振成像 弥散张量成像 磁共振波谱 

分 类 号：R739.41[医药卫生—肿瘤]