成人缺血缺氧性脑病MRI特征  

MRI features of adult hypoxic-ischemic encephalopathy

作　　者：安彦虹[1,2] 齐志刚 戎冬冬[1,2] 赵志莲 卢洁[1,2,3] AN Yanhong;QI Zhigang;RONG Dongdong;ZHAO Zhilian;LU Jie(Department of Radiology,Xuanwu Hospital Capital Medical University,Beijing 100053,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100053,China;Department of Nuclear Medicine,Xuanwu Hospital Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院放射科,北京100053 [2]磁共振成像脑信息学北京市重点实验室,北京100053 [3]首都医科大学宣武医院核医学科,北京100053

出　　处：《中国医学影像技术》2020年第6期818-822,共5页Chinese Journal of Medical Imaging Technology

基　　金：国家重点研发计划(2016YFC0107107);北京市科学技术委员会资助项目(Z171100000117001);北京市医院管理局“登峰”计划(DFL20180802)。

摘　　要：目的分析成人缺血缺氧性脑病患者的MRI表现及其特征。方法收集18例因各种原因导致缺血缺氧后接受MR检查患者,并对资料进行分析。结果18例中,17例MRI显示脑内异常信号,累及部位包括大脑皮层、皮层下白质、深部白质、侧脑室周围白质、胼胝体、基底核、海马、丘脑、脑桥及小脑;9例出现全脑萎缩,5例T1WI显示高信号,9例DWI显示扩散受限;5例接受MR增强检查,其中1例大脑皮层见脑回样轻度强化。1例MRI未见明显异常。结论MRI可发现缺血缺氧性脑病所致脑内广泛异常信号。MRI表现可反映脑缺血缺氧严重程度,并可用于预测治疗效果和评估预后。Objective To investigate the MRI features of adult hypoxic-ischemic encephalopathy.Methods Data of 18 patients who underwent MR scanning after ischemia and hypoxia due to various reasons were collected and analyzed.Results Among 18 patients,17 were found with abnormal MRI signals,involving cerebral cortex,subcortical white matter,deep white matter,lateral ventricle white matter,corpus callosum,basal ganglia,hippocampus,thalamus,pons and cerebellum.Diffuse brain atrophy was shown in 9 patients,while plain T1WI showed hyper-intensity along the cerebral cortex or basal ganglia in 5 cases.Restricted diffusion was shown on DWI in 9 cases.Enhanced MR scanning was performed in 5 patients and showed mild gyral enhancement in cerebral cortex in 1 patient.MRI showed no obvious lesion in 1 case.Conclusion MRI can display abnormal signals of hypoxic ischemic encephalopathy involving many brain regions.MRI features can not only reflect the severity of hypoxic-ischemic encephalopathy,but also predict treatment effect and evaluate the prognosis of patients.

关 键 词：缺氧缺血 脑 磁共振成像 成年人 

分 类 号：R742[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]