Primitive Neuroectodermal Tumor as the Second Malignant Neoplasm in a Long-Term Survivor Child of Acute Lymphoblastic Leukemia: A Case Report  

作　　者：Aoli Zhang Xiaojuan Chen Zhanqi Li Xiaofan Zhu 

机构地区：[1]Department of Pediatric Hematology,State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China [2]Department of Pathology,State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China [3]Department of Hematology,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China

出　　处：《Chinese Medical Sciences Journal》2020年第2期186-190,共5页中国医学科学杂志（英文版）

摘　　要：Acute lymphoblastic leukemia(ALL)is a common pediatric cancer.The second malignant neoplasms(SMNs)in long-term survivors of pediatric ALL are relatively rare.Herein we report a 10-year-old girl who was diagnosed as primitive neuroectodermal tumor(PNET)5 years after the initial diagnosis of ALL with radiotherapy・free treatment.PNET is an exceedingly rare neoplasm in SMNs of survivors of childhood ALL.It is predisposed to be misdiagnosed and the pathogenesis is unclear.The outcome is poor.Long-term follow-up is necessary for the survival children of ALL.

关 键 词：primitive neuroectodermal tumor second malignant neoplasms CHILDHOOD acute lymphoblastic leukemia 

分 类 号：R733.71[医药卫生—肿瘤]