Copper(I)-Catalyzed Interrupted Click/Sulfenylation Cascade:One-Pot Synthesis of Sulfur Cycle Fused 1,2,3-Triazoles  

作　　者：Weiguo Wang Shuai Huang Shikun Yan Xuejun Sun Chen-Ho Tung Zhenghu Xu 

机构地区：[1]School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu,Shandong 273165,China [2]Key Lab for Colloid and Interface Chemistry of Education Ministry,Shandong University,Jinan,Shandong 250100,China [3]State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China

出　　处：《Chinese Journal of Chemistry》2020年第5期445-448,共4页中国化学（英文版）

基　　金：support from the Natural Science Foundation of China and Shandong Province(Nos.21572118,21971149,ZR2018MB014,ZR2019ZD45);Tang scholar award and the Fundamental Research Funds of Shandong University.

摘　　要：Herein,we report a practical protocol for the synthesis of sulfur cycle fused 1,2,3-triazoles through a copper(I)-catalyzed tandem click/intramolecular sulfenylation reaction.The reaction proceeded via a copper-catalyzed alkyne azide cycloaddition,followed by interception of the in situ formed cuprate-triazole intermediate with p-toluenesulfonothioate.This reaction shows broad substrate scope,complete regioselectivity,and excellent functional group tolerance under mild reaction conditions.

关 键 词：reaction. CATALYZED COPPER 

分 类 号：O62[理学—有机化学]