中国强迫症状诱发图片库的建立  

Preliminary development of the Chinese Obsessive-Compulsive Symptom Provocation Picture Set

作　　者：刘一璠 王鹏翀 李占江 高见[1,2] 曹瑞想 陈群[1,2] 杨祥云 LIU Yifan;WANG Pengchong;LI Zhanjiang;GAO Jian;CAO Ruixiang;CHEN Qun;YANG Xiangyun(The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China;Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京安定医院,国家精神心理疾病临床医学研究中心,精神疾病诊断与治疗北京市重点实验室,北京100088 [2]人脑保护高精尖创新中心,首都医科大学,北京100069

出　　处：《中国心理卫生杂志》2020年第8期656-661,共6页Chinese Mental Health Journal

基　　金：国家自然科学基金——白质与强迫障碍:认知行为治疗的靶点与机制(81271493);北京市卫生局科研基金——强迫障碍前额叶皮层-纹状体-丘脑-皮层环路的功能连接与生化代谢物的关系(QML20181903)。

摘　　要：目的:初步建立中国强迫症状诱发图片库(COCPS)。方法:依据临床访谈法建立图片条目池,通过拍摄和开源图片网站收集图片1155张,经过筛选后初步形成图片库。招募28例强迫障碍患者和28例健康被试对图片从愉悦度、优势度、唤醒度、侵入性想法和行为冲动5个维度进行9级评分。结果:COCPS最终纳入278张有效图片,2组被试在5个维度指标上的图片评分具有较高的内部一致性(Cronbach'sα<均>0.91)。Mann-Whitney U检验表明,相比健康被试,患者组有更高的唤醒度[5(1,9)vs.4(1,9)]、侵入性想法[3(1,9)vs.2(1,9)]、行为冲动[5(1,9)vs.3(1,9)]评分,与更低的愉悦度[4(1,9)vs.5(1,9)]和优势度[5(1,9)vs.5(1,9)]评分(均P<0.001)。结论:中国强迫症状诱发图片库具有良好的症状诱发效果,可以用于对强迫障碍的相关研究。Objective:To develop the Chinese Obsessive-Compulsive symptom Provocation Picture Set(COCPS)preliminarily.Methods:Clinical interview was conducted to create an item pool of the picture set.A total of 1155 pictures were collected from open source websites and were shot from scenes in real-life scenarios.After screening,a picture set was established as a precursor to the present study.And 28 patients with OCD and 28 normal controls were recruited to evaluate the picture set from 5 dimensions including pleasure,dominance,arousal,intrusive thoughts,and the urge-to-act by rating on a 9-level scale.Results:Totally 278 pictures were included in the picture set.The rating score distribution on the 5 dimensions within the two groups had high internal consistency(all Cronbach'sα>0.91).Mann-Whitney U test revealed that OCD patients scored higher on the arousal[5(1,9)vs.4(1,9)],intrusive thought[3(1,9)vs.2(1,9)],urge-to-Act[5(1,9)vs.3(1,9)]dimensions and scored lower on the pleasure[4(1,9)vs.5(1,9)]and dominance[5(1,9)vs.5(1,9)]dimensions(Ps<0.001)than the normal controls.Conclusion:It suggests that COCPS could effectively induce obsessive and compulsive symptoms and could be used in studies of OCD.

关 键 词：强迫障碍 症状诱发 图片库 

分 类 号：R749.72[医药卫生—神经病学与精神病学]