脑部恶性肿瘤热消融治疗的现状研究  

Current Status of Thermal Ablation for Malignant Brain Tumors:A Review

作　　者：廖继芬(综述) 卢漫(审校) Liao Jifen;Lu Man(School of Medical Imaging,North Sichuan Medical College,Nanchong 737000,Sichuan,China;Medical Ultrasound Center,Sichuan Cancer Hospital&Institute,Sichuan Cancer Center,School of Medicine,University of Electronic Science and Technology of China,Chengdu 610041,Sichuan,China)

机构地区：[1]川北医学院医学影像学院,四川南充637000 [2]四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学医学院超声医学中心,成都610041

出　　处：《肿瘤预防与治疗》2020年第6期537-541,共5页Journal of Cancer Control And Treatment

基　　金：成都市科技项目-重点研发支撑计划(编号:2018-YF05-01445-SN)。

摘　　要：恶性脑肿瘤极具侵袭性,尽管随着医学的发展,恶性脑肿瘤已经有了很多种标准治疗方法,如手术、放疗和化疗等,但患者的平均生存时间仍然很短。热消融作为一种新兴的脑肿瘤治疗方式,目前已经在动物实验和人类的临床治疗中证明其有效性和优越性。随着影像学发展,融合成像导航的热消融治疗作为更前沿的脑肿瘤的新兴治疗手段,因其术前肿瘤定位、术中融合成像引导消融位置较深或不宜手术切除的脑肿瘤及消融引发积极免疫等优势,在恶性脑肿瘤治疗领域中得到广泛研究。在本综述中,我们主要总结几种主要的恶性脑肿瘤热消融方法的发展及现状。Malignant brain tumors are extremely aggressive.Despite medical advances in standard treatments for brain tumors such as surgery,radiation therapy,chemotherapy,and a combination of these treatments,the mean survival time of patients is still very short.Thermal ablation,as a new treatment method for brain tumors,has been proved effective and superior in animal experiments and clinical treatment for humans.With the development of medical imaging,the thermal ablation navigated by fusion imaging as a more frontier treatment for brain tumors has been widely studied in the field of malignant brain tumor treatment because of its advantages such as preoperative tumor localization,intraoperative fusion imaging-guided ablation of deep located or inoperable brain tumors,and positive immune responses to thermal ablation.In this review,we mainly review the development and status of thermal ablation for malignant brain tumors.

关 键 词：恶性脑肿瘤 热消融治疗 影像引导 

分 类 号：R739.41[医药卫生—肿瘤] R730.5[医药卫生—临床医学]