“五步脱敏疗法”在甲基苯丙胺成瘾患者中的应用效果初探  

Effects of Five-Step Desensitization Therapy in methamphetamine addicts:a pilot study

作　　者：陈家言[1,2,3] 王云翠 李帅奇 王增珍 CHEN Jiayan;WANG Yuncui;LI Shuaiqi;WANG Zengzhen(School of Public Health,Tongji Medical College,Huazhong University of Science and Technologyy,Wuhan,430030,China;School of Public Health,Nanchang University,Nanchang,330006,China;Jiangxi Province Key Laboratory of Preventive Medicine,Nanchang,330006,China;School of Nursing,Hubei University of Chinese Medicine,Wuhan,430065,China;Department of Children Hygiene,Third Affiliated Hospital of Zhengzhou University,Zhenzhou,450052,China;Tongji Research Center of Mental Health,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China)

机构地区：[1]华中科技大学同济医学院公共卫生学院,武汉430030 [2]南昌大学公共卫生学院,南昌330006 [3]江西省预防医学重点实验室,南昌330006 [4]湖北中医药大学护理学院,武汉430065 [5]郑州大学第三附属医院儿童保健科,郑州450052 [6]华中科技大学同济医学院心理卫生研究中心,武汉430030

出　　处：《中国药物依赖性杂志》2020年第2期117-123,共7页Chinese Journal of Drug Dependence

基　　金：国家自然科学基金面上项目(81573236)。

摘　　要：目的:探讨"五步脱敏疗法"对成瘾患者渴求、线索敏感及成瘾记忆的影响。方法:在湖北省武汉市3所自愿戒毒医院中招募39名甲基苯丙胺依赖患者,随机分配入干预组和对照组。干预组接受连续5天,每天90分钟的"五步脱敏"治疗,在此期间对照组不干预。分别采用"渴求视觉模拟标尺"(VAS)、"线索敏感问卷"(CSQ)和"成瘾记忆强度量表"(AMIS)对患者的渴求、毒品相关线索敏感性及成瘾记忆强度进行测试。结果:研究对象的VAS得分变化存在组别和时间的交互效应(P=0.005),CSQ和AMIS得分变化均存在组别效应(P<0.05)。接受干预后,干预组各测量指标得分均低于对照组。结论:"五步脱敏"治疗可有效降低成瘾患者的渴求水平、对毒品相关线索的敏感程度及其成瘾记忆强度。Objective:To explore the effects of Five-Step Desensitization Therapy(FSDT)on craving,drug-related cue sensitization,and addiction memory among methamphetamine addicts.Methods:A total of 39 methamphetamine addicts were recruited from three hospitals in Wuhan,Hubei Province,and were randomly assigned to be as an intervention group or a control group.Participants in the intervention group received a 5-day(90 min per day)FSDT intervention,while those in the control group waited during this period without intervention.Respectively,the Visual Analogue Scale(VAS),Cue-Sensitization Questionnaire(CSQ),and Addiction Memory Intensity Scale(AMIS)were used to measure the participants′craving,cue reactivity to drug-related stimuli,and their intensity of addiction memory.Results:Interaction effects of intervention and time were found significantly on the VAS scores(P=0.005).Intervention effects were found significantly on scores of the CSQ and AMIS(P<0.05).For participants in the intervention group,scores of the VAS,CSQ,and AMIS were significantly less than those in the control group after treatment.Conclusion:The FSDT intervention can decrease the methamphetamine addicts′craving and reduce their cue reactivity to drug-related stimuli as well as the intensity of addiction memory.

关 键 词：眼动脱敏与再加工 内观 催眠 神经语言模式 渴求 线索敏感 成瘾记忆 

分 类 号：R749[医药卫生—神经病学与精神病学]