前庭性偏头痛患者的前庭功能变化及特点分析  

Characteristics and Changes of Vestibular Function in Patients with Vestibular Migraine

作　　者：祁晓媛 范桂梅[1] 贾鸿宁 吴慧君[1] 姚玉芳 张丽华[1] QI Xiaoyuan;FAN Guimei;JIA Hongning;WU Huijun;YAO Yufang;ZHANG Lihua(Department 4 of Neurology,Cangzhou Central Hospital,Cangzhou 061000,Hebei,China)

机构地区：[1]沧州市中心医院神经内四科,河北沧州061000

出　　处：《贵州医科大学学报》2020年第7期854-858,共5页Journal of Guizhou Medical University

基　　金：沧州市科学技术研究与发展指导计划项目(172302101)。

摘　　要：目的:分析前庭性偏头痛(VM)患者的前庭功能变化及特点。方法:选取神经内科门诊或住院VM患者92例作为VM组,同期入院体检健康志愿者50例作为正常组,收集和分析VM组患者的临床特点,采用纯音测听、声导抗、冷热试验、摇头试验(HSN)、颈肌前庭诱发肌源性电位(cVEMP)及前庭自旋转试验(VAT)比较和分析2组受检者异常率的检出情况。结果:VM组患者前庭症状持续时间<1 min~>1 d不等,患者自发性眩晕或位置性眩晕症状,以1 h^1 d最为常见(46.74%),伴发症状由多到少依次为偏头痛74例(80.43%)、畏声49例(53.26%)、畏光46例(50.00%)及视觉先兆33例(35.87%);VM组患者纯音平均听阈、高频平均听阈、冷热试验、摇头试验、cVEMP和VAT的异常率均高于正常组,差异均有统计学意义(P<0.05);83.70%VM组患者至少出现1项上述前庭功能检查异常。结论:大部分VM患者存在前庭功能异常,加强前庭功能检测有助于VM和其他前庭性疾病的评估诊断。Objective:To investigate the characteristics and changes of vestibular function of patients with vestibular migraine(VM)diagnosed according to the Baray Society standard.Methods:92 patients with VM were selected from the outpatient department and inpatient department of Neurology as VM group,and 50 healthy volunteers as the normal group.The clinical characteristics of VM group were observed and analyzed.The abnormality rates of both groups were compared and analyzed through the pure tone audiometry,acoustic immittance,cold and hot test,head-shaking nystagmus test(HSN),cervical vestibular evoked myogenic potential(cVEMP)and vestibular autorotational test(VAT).Results:In VM group,the duration of vestibular symptoms varied from less than 1 min to more than 1 day,and the most common symptoms were spontaneous vertigo or positional vertigo(46.74%),74 migraine(80.43%),49 fear of sound(53.26%),46 photophobia(50.00%)and 33 visual aura(35.87%);The abnormality rates of pure tone average hearing threshold,high frequency average hearing threshold,cold and hot test,HSN,cVEMP and VAT in VM group were higher than those in the normal group.The difference was statistically significant(P<0.05);83.70%of VM patients had at least one item with abnormal vestibular function.Conclusion:Most patients with VM have vestibular dysfunction.Vestibular function tests contribute to the evaluation and diagnosis of VM and other vestibular diseases.

关 键 词：眩晕 前庭功能试验 前庭性偏头痛 临床特点 颈肌前庭诱发肌源性电位 前庭自旋转试验 

分 类 号：R747.2[医药卫生—神经病学与精神病学] R764.34[医药卫生—临床医学]