胃癌5、6组淋巴结转移危险因素分析  

Analysis of risk factors for lymph node groups 5 and 6 metastasis in gastric cancer

作　　者：王子豪 曹亮[1] 梁品[1] 刘革[1] 张驰[1] 张健[1] 尹逊国[1] 刘焕然[1] 刘严峰[1] 胡祥[1] WANG Zihao;CAO Liang;LIANG Pin;LIU Ge;ZHANG Chi;ZHANG Jian;YIN Xunguo;LIU Huanran;LIU Yanfeng;HU Xiang(Department of Gastrointestinal Surgery,The First Affiliated Hospital of Dalian Medical Universi/y,Liaoning Dalian.116011,China)

机构地区：[1]大连医科大学附属第一医院胃肠外科,辽宁大连116011

出　　处：《外科理论与实践》2020年第3期217-221,共5页Journal of Surgery Concepts & Practice

摘　　要：目的 :分析胃癌下缘距幽门的长度和Borrmann分型与5、6组淋巴结转移的相关性。方法 :374例胃癌分为5、6组淋巴结转移阳性组和阴性组。分析可预测5、6组淋巴结转移阳性的肿瘤下缘距幽门长度临界值。分析胃癌5、6组淋巴结转移的危险因素。进一步分析T1期与T2期(BorrmannⅡ型)胃癌的5、6组淋巴结转移的差异。结果:肿瘤下缘距幽门长度可预测胃癌5、6组淋巴结转移,临界值为3.75 cm。胃癌下缘距幽门长度>3.75 cm时淋巴结转移率为11.1%。肿瘤下缘距幽门的长度、Borrmann分型、分化程度、浸润深度、分期是5、6组淋巴结转移的独立危险因素。肿瘤下缘距幽门长度>3.75 cm时,T1期与T2期(BorrmannⅡ型)胃癌5、6组淋巴结转移差异无统计学意义(P>0.05)。结论:当肿瘤下缘距幽门长度>3.75 cm时,T1期与T2期(BorrmannⅡ型)胃癌5、6组淋巴结转移相似。Objective To analyze the correlation of both the distance from lower edge of gastric cancer to pylorus and the Borrmann classification with metastasis of lymph node groups(LNG)5(suprapyloric)and 6(infrapyloric).Methods There were 374 cases with gastric cancer including the group with LNG 5 and 6 metastasis and the group without LNG 5 and 6 metastasis.The critical ditance from lower edge of gastric cancer to pylorus which predicted LNG 5 and 6 metastasis was analyzed combined with the risk factors for LNG 5 and 6 metastasis.LNG 5 and 6 metastasis in patients with gastric cancer stage T1 and T2(BorrmannⅡ)was analyzed.Results LNG 5 and 6 metastasis in patients with gastric cancer could be predicted using distance from lower edge of tumor to pylorus with the critical distance 3.75 cm.The rate of lymph node metastasis was 11.1%when the distance from lower edge to pylorus was longer than 3.75 cm.The independent risk factors for LNG 5 and 6 metastasis were gotten including the distance from the lower edge of tumor to pylorus,Borrmann classification,extent of differentiation of cancer,depth of infiltration,and gastric cancer stage.There was no statistical difference in metastasis of LNG 5 and 6 between stage T1 and stage T2(BorrmannⅡ)of gastric cancer when the distance from lower edge of tumor to pylorus was longer than 3.75 cm(P>0.05).Conclusions There was no difference in LNG 5 and 6 metastasis between T1 and T2(BorrmannⅡ)gastric cancer,when the distance from lower edge of tumor to pylorus was longer than 3.75 cm.

关 键 词：胃癌 淋巴结转移 BORRMANN分型 

分 类 号：R735.2[医药卫生—肿瘤]