心脏彩超联合N末端B型利钠肽原评估不同分级肝硬化患者心功能的研究  

Study on echocardiography combined with NT-proBNP in evaluating cardiac function in patients with different grades of cirrhosis

作　　者：秦宪涛 刘广勇[1] 姜文营 王振峰[1] 常方圆[2] Qin Xiantao;Liu Guangyong;Jiang Wenying;Wang Zhenfeng;Chang Fangyuan(Department of General Surgery,the Second People's Hospital of Liaocheng City,Shandong Liaocheng;Department of Cardiology,the Second People's Hospital of Liaocheng City,Shandong Liaocheng 252601)

机构地区：[1]聊城市第二人民医院普外科,山东聊城252601 [2]聊城市第二人民医院心内科,山东聊城252601

出　　处：《中国社区医师》2020年第19期115-116,共2页Chinese Community Doctors

摘　　要：目的:探讨心脏彩超联合N末端B型利钠肽原(NT-proBNP)评估不同分级肝硬化患者心功能的临床意义。方法:2017年1月-2017年12月收治肝硬化患者50例,根据肝功能Child-Pugh分级分为A组(15例)、B组(22例)、C组(13例)。三组患者均进行心脏彩超检查和NT-proBNP检测,并比较检测结果。结果:A组左室射血分数(LVEF)及E/A均高于B组、C组,且B组高于C组,差异均有统计学意义(P<0.05);A组血浆NT-proBNP水平低于B组、C组,且B组低于C组,差异均有统计学意义(P<0.05)。结论:肝硬化患者心功能损害程度与肝功能有关,心功能损害程度随着肝功能受损程度而加重。Objective:To explore the clinical significance of cardiac function evaluation in patients with different grades of cirrhosis by echocardiography combined with NT-proBNP.Methods:From January 2017 to December 2017,50 patients with cirrhosis were enrolled,they were divided into A group(n=15),B group(n=22)and C group(n=13)according to the Child-Pugh classifications of liver function.Echocardiography and NT-proBNP tests were performed in all three groups and the results were compared.Results:Left ventricular ejection fraction(LVEF)and E/A ratio in A group were higher than B group and C group,and B group was higher than C group,the differences were statistically significant(P<0.05).Plasma NT-proBNP level in A group was lower than B group and C group,and B group was lower than C group,the differences were statistically significant(P<0.05).Conclusion:The degree of cardiac function damage of patients with cirrhosis is related to liver function,and the degree of cardiac function damage is aggravated with the degree of liver function damage.

关 键 词：肝硬化 心脏彩超 NT-PROBNP 心功能 

分 类 号：R575.2[医药卫生—消化系统] R445.1[医药卫生—内科学]