阿司匹林抗肝癌的作用机制及临床研究进展  

Mechanism and clinical research progress of aspirin against liver cancer

作　　者：费锐 刘磊(综述)[1] 刘伟(审校)[1] FEI Rui;LIU Lei;LIU Wei(The First College of Clinical Medical Science,China Three Gorges University,Institute of Digestive Disease,China Three Gorges University,Department of Gastroenterology,Yichang Central People’s Hospital,Yichang Hubei 443000,China)

机构地区：[1]三峡大学第一临床医学院,三峡大学消化疾病研究所,宜昌市中心人民医院消化内科,湖北宜昌443000

出　　处：《临床与病理杂志》2020年第6期1572-1578,共7页Journal of Clinical and Pathological Research

基　　金：国家自然科学基金(NO.31600134)。

摘　　要：目前肝癌是我国和全球发病率及病死率都很高的恶性肿瘤之一,且治疗效果差,给患者带来了沉重的经济负担。阿司匹林作为一种古老的药物,对包括肿瘤在内的许多疾病都有疗效。在临床回顾、基础研究中,又发现了其对肝癌有确切的预防和治疗作用。几十年来,关于阿司匹林抗肝癌的机制逐渐被揭示。Liver cancer is one of the malignant tumors with high morbidity and mortality in the world and China with poor treatment effect, which brings a heavy economic burden to patients. As an ancient drug, aspirin has been found to have many miraculous therapeutic effects against many diseases including tumors. In clinical review and basic research, it has been found to have a definite preventive and therapeutic effect on liver cancer. For decades,mechanism of anti-hepatocarcinoma by aspirin has been gradually revealed.

关 键 词：肝癌 阿司匹林 作用机制 

分 类 号：R735.7[医药卫生—肿瘤]